Tooth Sensitivity

2

Review clinical trials related to Tooth Sensitivity. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Graphene-Reinforced CAD/CAM Restorations for MIH-Affected Molars in Adolescents: A Prospective Clinical Study

This study evaluates the clinical performance, marginal integrity, surface wear, color stability, and postoperative sensitivity of graphene-reinforced CAD/CAM indirect restorations (inlays, onlays, overlays) in molars affected by moderate to severe Molar-Incisor Hypomineralization (MIH) in adolescents. A total of 30 patients aged 10-16 years will receive minimally invasive indirect restorations fabricated from a nano-reinforced graphene polymer (G-CAM®). Clinical outcomes will be assessed using FDI criteria, VAS sensitivity scores, patient satisfaction, and digital 3D scans over a 12-month follow-up. The study aims to determine clinical acceptability and safety compared with historical outcomes reported for composite and lithium-disilicate indirect restorations.

Participants needed: 30
Trial details
Age: 10-16Biological sex: AllType: InterventionalSponsor: Universitat Internacional de CatalunyaUpdated: Jan 9, 2026Locations: 1
Eligibility criteria

Adolescents aged 10-16 years. [+4]

Fluorosis, amelogenesis imperfecta, or other enamel defects. [+6]

Status: Recruiting

The Effect of Bleaching Application Mode on Bleaching-induced Tooth Sensitivity.

The aim of this study is to evaluate the effect of single versus multiple application protocols for in-office dental bleaching using two different bleaching gels (Pola Office Plus, SDI, 37.5% HP and Opalescence Boost, Ultradent, 40% HP) on the risk and intensity of tooth sensitivity, as well as the effect of the application protocol on the bleaching efficacy. Null hypothesis: There is no difference in intensity and risk of tooth sensitivity between single and multiple application of each gel and the application protocol dose not present significant effect on the bleaching efficacy.

Participants needed: 60
Trial details
Age: 18-35Biological sex: AllType: InterventionalSponsor: King Abdullah University HospitalUpdated: Sep 15, 2025Locations: 1
Eligibility criteria

At least eight maxillary anterior teeth present. [+7]

Active caries and/or periodontal diseases (gingivitis and recession) or wasting... [+4]