Health Trials

Transthyretin Amyloidosis (ATTR) With Cardiomyopathy

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Review clinical trials related to Transthyretin Amyloidosis (ATTR) With Cardiomyopathy. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

MAGNITUDE: A Phase 3 Study of NTLA-2001 in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR-CM)

To evaluate the efficacy and safety of a single dose of NTLA-2001 compared to placebo in participants with ATTR-CM.

Participants needed: 1,200
Trial details
Phase: Phase 3Age: 18-90Biological sex: AllType: InterventionalSponsor: Intellia TherapeuticsUpdated: Mar 27, 2026Locations: 132
Eligibility criteria

Documented diagnosis of ATTR amyloidosis with cardiomyopathy [+3]

New York Heart Association (NYHA) Class IV HF [+9]

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