Trauma (Including Fractures)

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Review clinical trials related to Trauma (Including Fractures). Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Mortality of Trauma in the Intensive Care Unit.

In this study, it was planned to establish the factors associated with severe trauma discharged from the intensive care unit and mortality. A cross-sectional trial will be conducted to review the ICU discharge database at a two-year interval to review records of trauma admissions patients and compare them with other types of admissions. Participant institutions are general hospitals (public and private) from the Colombian Orinoco region. the prevalence of admission by trauma will also be determined.

Participants needed: 500
Trial details
Age: 15-100Biological sex: AllType: ObservationalSponsor: Hospital Departamental de VillavicencioUpdated: May 27, 2026Locations: 1
Eligibility criteria

Admitted to the intensive care unit.

None.

Status: Not yet recruiting

Tru-Vu Wrist Positioning Aid Multi-Center Implementation Within NLHS

This study has two primary aims: 1) to determine whether a novel wrist x-ray positioning aid can be implemented within 3 different healthcare centers in Newfoundland and Labrador, and 2) to determine the ability of the tool to improve patient positioning in wrist x-rays. It will also learn about the number of repeat x-rays required with or without the use of the tool and radiographer confidence. The main questions it aims to answer are: 1. Will the implementation of the Tru-Vu differ between an urban health center, rural clinic, and remote regional hospital? 2. Can the Tru-Vu improve the positioning procedure for radiographers performing wrist x-rays, resulting with more useful x-rays. Researchers will compare x-rays before and after the implementation of the tool as well as between centers. Technologist participants will: * Use the tool during the positioning procedure for wrist x-rays. * Provide feedback regarding tool use and perceived implementation barriers and facilitators.

Participants needed: 1,800
Trial details
Phase: Phase 3Age: 18+Biological sex: AllType: InterventionalSponsor: Western UniversityUpdated: May 18, 2026Locations: 3
Eligibility criteria

Must be 18 years of age or older [+2]

Incapable of providing informed consent

Status: Recruiting

Renal and Hepatic Abnormal Doppler Patterns in Trauma

The goal of this observational study is to learn about renal and hepatic blood flow abnormalities detected by bedside ultrasound in adult patients admitted to the intensive care unit (ICU) following major trauma. The main questions it aims to answer are: * How reliably can trained operators measure renal Doppler and venous congestion scores (RDRI and VExUS) across different hospitals? * How common are abnormal kidney and liver blood flow patterns in major trauma patients during the first 72 hours of ICU admission? * Are these abnormal patterns associated with acute kidney injury or the need for mechanical ventilation? Participants admitted to ICUs or high-dependency units (HDUs) with major trauma (Injury Severity Score \>15) will undergo non-invasive bedside ultrasound assessments at admission and at 24, 48, and 72 hours. No additional treatments or interventions will be given as part of this study. Kidney function will also be checked at 6 months after hospital discharge.

Participants needed: 350
Trial details
Age: 18-65Biological sex: AllType: ObservationalSponsor: Azienda Usl di BolognaUpdated: Mar 25, 2026Locations: 1
Eligibility criteria

Age 18-65 years; [+2]

Age <18 or >65; [+4]

Status: Not yet recruiting

Negative Pressure Wound Therapy as a Predictor of Persistent Pain After War-Related Trauma

War-related trauma frequently causes complex soft tissue injuries that require repeated surgical treatment and advanced wound management techniques such as Negative Pressure Wound Therapy (NPWT). Although NPWT is widely used to promote wound healing and prepare wounds for reconstruction, its relationship with long-term pain outcomes remains unclear. This prospective cohort study aims to investigate whether the use of NPWT after war-related trauma is associated with an increased risk of persistent post-traumatic pain six months after injury. Adult patients with traumatic soft tissue injuries requiring surgical management will be enrolled and followed for six months. In addition to NPWT exposure, the study will evaluate several early clinical predictors of chronic pain, including acute pain intensity, number of surgical debridements, suspected nerve injury, and mechanism of trauma. Understanding these predictors may help clinicians identify high-risk patients early and develop targeted strategies for pain prevention and rehabilitation after severe trauma.

Participants needed: 150
Trial details
Age: 18-60Biological sex: AllType: ObservationalSponsor: Charitable Organisation Charitable Fund Superhumans (Co Cf Superhumans)Updated: Mar 18, 2026Locations: 1
Eligibility criteria

age ≥18 years [+4]

chronic pain in the same anatomical region prior to injury [+4]

Status: Not yet recruiting

5 Minute 'HOT' Trauma CT Rates Of Detection Study

Many injured patients receive urgent CT imaging to identify major injury. CT imaging of trauma patients is often time critical and the accurate detection of life-threatening findings on this CT is essential. Often following a scan a radiologist is not immediately available to review the imaging, however other members of the trauma team have access to the imaging and may be in a position to provide a "hot" report. In this study we aim to demonstrate if an educational intervention with a checklist improves accuracy of the hot report.

Participants needed: 300
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: University Hospital Plymouth NHS TrustUpdated: Jan 12, 2026Locations: 1
Eligibility criteria

Medical professionals involved in trauma image review. [+2]

Unable to review CT imaging due to lack of previous experience or disability tha... [+2]

Status: Not yet recruiting

Assess the Efficacy of Tailored Patient Information and Voluntary Patient-managed Outpatient Digital Follow-up (I-POD) as an Adjunct to Standard Treatment According to National Guidelines in the National Trauma Plan Among Adult Trauma Patients in Norway.

The POSTRAUMA trial is a clinical trial at The Regional trauma centre of Western Norway, Haukeland University Hospital. Trauma is the leading cause of death worldwide in patients aged 1-45 years. In Norway, approximately 10,000 patients are admitted to hospital annually due to trauma, with 66% being male. The mean age is 43 years for male and 48 years for female, indicating a relatively young patient population. While mortality rates are decreasing, a significant proportion of trauma survivors experience long-term disabilities, reduced quality of life, and difficulties in returning to work. These consequences impose substantial burdens on individuals, families, and society. Considering these issues, a shift in focus is needed-from survival alone to long-term functional recovery and quality of life after trauma. Severe trauma often requires long-term follow-up, both physically and psychosocially. Traditional follow-up can be fragmented and not tailored to individual needs. Digital patient monitoring and tailored information have the potential to improve patient pathways, but knowledge about how these are experienced by patients is limited. The goal is to find out if Norwegian trauma patients who receive tailored patient information and patient-managed outpatient digital follow-up, in addition to standard treatment have: * Less disability * Return more often to work * Improved quality of life The study population are Norwegian trauma patients, 16 years or older at date of inclusion, who are admitted to Haukeland University hospital (HUS) following trauma with trauma team activation. 256 patients will be included in this trial. Participants will: * Answer a questionnaire at inclusion, one month, 6 months and 12 months. * Participants in the intervention group will be invited to digital outpatient follow up one month after the accident. * Some participants will be interviewed about how they experienced their trauma follow up.

Participants needed: 256
Trial details
Age: 16+Biological sex: AllType: InterventionalSponsor: Haukeland University HospitalUpdated: Dec 22, 2025Locations: 1
Eligibility criteria

16 years or older [+3]

15 years or younger [+7]

Status: Recruiting

Assessment of the Feasibility of Using a Preoperative Surgical Fracture Analysis Tool

This study aims to evaluate a preoperative fracture analysis tool that uses 3D visualization and biomechanical modeling to assist surgeons in planning screw and plate fixation for complex tibial plateau fractures. By simulating different fixation strategies based on patient-specific CT data, the tool provides insights into construct stability, potentially improving surgical precision and reducing intraoperative uncertainty. The study also investigates the tool's feasibility within current clinical workflows without altering the standard of care.

Participants needed: 40
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Brigham and Women's HospitalUpdated: Sep 26, 2025Locations: 2
Eligibility criteria

Age above 18 [+1]