Treatment of Resistant Depression

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Review clinical trials related to Treatment of Resistant Depression. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Theta Burst Stimulation With an 8-Coil Versus H1-Coil for Resistant Depression

The goal of this clinical trial is to compare response rates after treatment with Figure Eight-Coil TMS versus H-Coil TMS on the prefrontal cortex left dorsolateral, in patients suffering from depression resistant. The main question it aims to answer is: rTBS (accelerated neuronavigated intermittent Theta Burst Stimulation) is more effective than hTBS (accelerated deep intermittent Theta Burst Stimulation) in the treatment of resistant depression in terms of response rate.? Researchers will compare Figure Eight-Coil TMS (rTBS) versus H-Coil TMS (hTBS) to see if rTBS is more effective than hTBS. Participants will: * Receive, for each stimulation method, 8 sessions per day spaced 50 minutes apart, over 5 days. * Have visit all day of stimulation for checkups and tests. * Have a a research MRI before and after treatment. * Have follow-up visits at 1 month, 2 months, 3 months, 6 months, and 12 months post-treatment, via teleconsultation.

Participants needed: 108
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Dominique JANUELUpdated: Feb 6, 2025
Eligibility criteria

Patients over 18 years of age [+5]

Presence of a contraindication to TMS: epilepsy, intracranial foreign body, coch... [+11]