Tricuspid Insufficiency

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Review clinical trials related to Tricuspid Insufficiency. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

PASCAL Precision-GDMT Registry

The goal of this observational study is to demonstrate that successful tricuspid valve repair with the PASCAL Precision System in participants with at least severe tricuspid insufficiency and left ventricular dysfunction will be associated with an improvement in up-titration of guideline-directed medical therapy (GDMT). The main question it aims to answer is: Does the tricuspid insufficiency repair with the Pascal Precision System increases the dose of the medications used for heart failure therapy in the study population 12 months after tricuspid repair, as compared to the dose taken at baseline. Participants undergoing tricuspid repair and fulfilling all inclusion/exclusion criteria will be asked to answer heart failure assessment as well as quality of life questionnaires at baseline and at 12 months post intervention. Medication monitoring will be performed throughout the study.

Participants needed: 50
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Ceric SàrlUpdated: May 13, 2026Duration: 12 Months
Eligibility criteria

Participants of age ≥ 18 years [+5]

Anatomy unsuitable for TEER as determined by local heart team [+13]

Status: Recruiting

Influence of Lung Ultrasonography on the Prognosis and Postoperative Outcomes in Cardiac Surgical Patients

The goal of this interventional is to assess advantages of the ultrasound examination of the lungs in the early postoperative period in cardiac surgical patients after heart surgeries requiring cardiopulmonary bypass. Evaluation of pulmonary complications and outcomes during mid-term follow-up, as well as comparison of ultrasound examination and traditional roentgenologic methods (X-ray examination and CT of the chest) will be performed. The main question\[s\] it aims to answer are: * Is ultrasound examination of the lungs a more specific and sensitive method in identification of early postoperative pulmonary complications after on-pump cardiac surgical procedures, in comparison with traditional X-ray methods. * Does early identification of interstitial pulmonary edema (based on number of visualised B-lines in the early postoperative period), influences mid-term outcomes in this cohort of patients Participants will undergo ultrasound examination of the lungs on postoperative day 1, 3, 5 and 7 after heart surgery. Based on ultrasound findings and degree of interstitial pulmonary edema, medical (diuretics, anti-inflammatory, e.t.c) therapy will be modified. Researchers will compare this group of patients with control group, in which ultrasound examination will be performed in the same time frames, but no changes in medical management based on ultrasound findings will be made to see if timely administered medical therapy, based on ultrasound findings, can significantly improve symptoms, hospital lengths of stay and outcomes of this patients.

Participants needed: 186
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Saint Petersburg State University, RussiaUpdated: Dec 9, 2024Locations: 1
Eligibility criteria

open heart surgery with cardiopulmonary bypass (CPB) between 15 December 2023 an... [+1]

reoperations on the open heart with CPB [+4]

Status: Recruiting

Retrospective Prospective Multicentric Clinical Follow up of Patients After Being Treated With TricValve®

Retrospective prospective Multicentric clinical follow up of patients with severe tricuspid regurgitation after being treated with the TricValve® Transcatheter Bicaval Valves System.

Participants needed: 450
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: P+F Products + Features GmbHUpdated: Apr 3, 2024Locations: 28Duration: 5 Years
Eligibility criteria

Successful treatment with TricValve Transcatheter Bicaval Valves System [+1]

no exclusion criterion