Ulcer, Gastric

3

Review clinical trials related to Ulcer, Gastric. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Marginal Ulcer Healing With Low-Thermal Argon Plasma Endoscopic Treatment

The objective of the study is to investigate the treatment of marginal ulcers with Low Thermal plasma in an endoscopic setting. By a treatment of the ulcerated areas with argon plasma with low power settings (\~ 1 W) we hypothesize that the size of the ulcers will shrink, and the healing is accelerated compared to standard of care alone. Patients will benefit from this minimally invasive approach compared to a much more invasive surgical approach that comes with higher risks and hospital stay length time. From a societal and scientific perspective, this study aims to extend the well-documented clinical benefits of plasma technology - from external wound healing to internal ulcer treatment - within an endoscopic framework. The success of this study could pave the way for broader applications of LTP in the treatment of other endoscopically accessible conditions such as peptic ulcers, duodenal ulcers and esophageal ulcers. This advancement has the potential not only to improve patient outcomes through less invasive methods, but also to position LTP as a cornerstone in the future of gastroenterological wound management strategies.

Participants needed: 100
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Christopher C. Thompson, MD, MScUpdated: Jun 25, 2026Locations: 1
Eligibility criteria

Subjects aged 18 years and above, inclusive of both males and females. [+7]

Inability to provide informed consent. [+6]

Status: Recruiting

The Bioavailability and Effect on Pouch pH of Esomeprazole After Gastric Bypass

The objective of this study is to investigate the effect of Esomeprazol administered in tablets (Esomeprazol MUT Sandoz® 40mg) or in solution (Esomeprazol MUT Sandoz® 40mg in 10ml tap water) on acid production in the gastric pouch by measuring the intragastric pH and the serum concentration of esomeprazole.

Participants needed: 50
Trial details
Phase: Phase 4Age: 18+Biological sex: AllType: InterventionalSponsor: Prof Urs ZinggUpdated: Jun 9, 2026Locations: 1
Eligibility criteria

Proximal Roux-en-Y gastric bypass with linear stapled anastomosis 12 months prio... [+5]

Known intolerance or allergy for Esomeprazol [+3]