Ulcerative Colitis, Active Severe

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Review clinical trials related to Ulcerative Colitis, Active Severe. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

LY4268989 in Adults With Moderately to Severely Active Ulcerative Colitis

The main purpose of this study is to evaluate the safety and effectiveness of LY4268989 when compared to placebo in adult participants with moderately to severely active ulcerative colitis (UC). The study drug will be administered orally. The study will last up to approximately 108 weeks, excluding screening.

Participants needed: 1,431
Trial details
Phase: Phase 2Age: 18-80Biological sex: AllType: InterventionalSponsor: Eli Lilly and CompanyUpdated: Jun 23, 2026Locations: 253
Eligibility criteria

Have had an established diagnosis of ulcerative colitis (UC) for ≥3 months prior... [+5]

Have a current diagnosis of [+8]