Ulcerative Colitis Chronic

3

Review clinical trials related to Ulcerative Colitis Chronic. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

A Master Protocol (AMAZ): A Study of Mirikizumab (LY3074828) in Pediatric Participants With Ulcerative Colitis or Crohn's Disease (SHINE-ON)

The main purpose of this study is to evaluate the long-term efficacy of mirikizumab in pediatric participants with ulcerative colitis (UC) or Crohn's disease (CD). The study will last about 172 weeks and may include up to 44 visits. Additional treatment may be available to participants via a Continued Access Period.

Participants needed: 150
Trial details
Phase: Phase 3Age: 2-19Biological sex: AllType: InterventionalSponsor: Eli Lilly and CompanyUpdated: Jun 23, 2026Locations: 68
Eligibility criteria

Participants from originating studies (I6T-MC-AMBA [NCT05784246], I6T-MC-AMBU [N... [+2]

Participants must not have developed a serious adverse event (SAE) or Adverse Ev... [+5]

Status: Recruiting

R-3750 in Patients With Mild to Moderate Ulcerative Colitis

The goal of this study is to determine the safety and tolerability of orally taken probiotic (R-3750) in patients with mild to moderate ulcerative colitis. Patients will take an oral dosage of probiotic (R-3750) and provide patient-reported and physician scored measures of their colitis. Blood and fecal evaluations of inflammation and assessment of probiotic (R-3750) on fecal levels will also be measured.

Participants needed: 36
Trial details
Phase: Phase 1Age: 18-65Biological sex: AllType: InterventionalSponsor: Rise Therapeutics LLCUpdated: Jun 12, 2026Locations: 5
Eligibility criteria

18-65 years of age [+6]

Pregnancy, planned pregnancy, breastfeeding women [+17]

Status: Recruiting

A Study of Eltrekibart and Mirikizumab in Adult Patients With Moderately to Severely Active Ulcerative Colitis

The main purpose of this study is to determine the safety and efficacy of eltrekibart and mirikizumab in adult participants with moderately to severely active ulcerative colitis (UC).

Participants needed: 140
Trial details
Phase: Phase 2Age: 18-75Biological sex: AllType: InterventionalSponsor: Eli Lilly and CompanyUpdated: Apr 20, 2026Locations: 207
Eligibility criteria

Have had an established diagnosis of UC of ≥3 months in duration before baseline... [+4]

Have received anti-interleukin (IL)-23p19 or anti-IL-12p40 antibodies in the pas... [+4]