Unresectable Locally Advanced or Metastatic Solid Tumors

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Review clinical trials related to Unresectable Locally Advanced or Metastatic Solid Tumors. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

IBI3014 in Participants With Unresectable Locally Advanced or Metastatic Solid Tumors

This is a phase 1/2 multicenter, multi-regional, open-label, first-in-human study of IBI3014 in participants with unresectable locally advanced or metastatic solid tumors.

Participants needed: 250
Trial details
Phase: Phase 1, Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Innovent Biologics (Suzhou) Co. Ltd.Updated: Jan 29, 2026Locations: 3
Eligibility criteria

1.Participants with the ability to understand and give written informed consent... [+6]

1.Drugs and other treatments to be excluded; [+19]

Status: Not yet recruiting

Safety and Efficacy of SYHA1813 Single Agent or in Combination With Different Regimens in Unresectable Locally Advanced or Metastatic Solid Tumors.

This is an open-label, multi-center, multi-cohort, phase Ib/II clinical trial, divided into 8 cohorts according to tumor types. Cohorts 1-4 are SYHA1813 combined with different regimens, including safety run-in stage and cohort expansion stage. Cohorts 5-8 are SYHA1813 monotherapy and only include the expansion cohorts. The primary objective was to evaluate the safety and efficacy of SYHA1813 single agent or in combination with different regimens in unresectable locally advanced or metastatic solid tumors.

Participants needed: 380
Trial details
Phase: Phase 1, Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Shanghai Runshi Pharmaceutical Technology Co., LtdUpdated: Nov 12, 2024
Eligibility criteria

Aged >= 18 years; [+4]

Patients who are known or suspected to be allergic to the test drug or its compo... [+16]