Urinary Bladder Neurogenesis

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Review clinical trials related to Urinary Bladder Neurogenesis. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

A Randomized, Placebo-controlled Trial of Nitrous Oxide During In-office Bladder Botox Injections

The goal of this clinical trial is to assess if a mix of nitrous oxide and oxygen can improve pain control during bladder Botox injections. The primary question it aims to answer is: Does using nitrous oxide lower the overall level of pain during the procedure? Researchers will compare a 50:50 nitrous oxide/oxygen mixture (administered with the Pro-Nox system) plus standard care (with lidocaine in the bladder) to sham mask plus standard care to see if nitrous oxide works better for lowering pain. Participants will: * Receive their bladder Botox injection in the office setting * Either use nitrous oxide/oxygen plus standard care during the procedure, or sham mask plus standard care * Answer brief questions about pain, anxiety, satisfaction, and willingness to repeat the procedure

Participants needed: 96
Trial details
Phase: Phase 4Age: 18+Biological sex: FemaleType: InterventionalSponsor: TriHealth Inc.Updated: Feb 4, 2026Locations: 2
Eligibility criteria

Adult women ≥18 years old scheduled for in-office intradetrusor botulinum toxin...

Known/suspected vitamin B12 or folate deficiency or high-risk state (e.g., perni... [+7]