Status: Recruiting
Study of Subretinally Injected AAVB-081 in Patients With Usher Syndrome Type IB (USH1B) Retinitis Pigmentosa
The purpose of the 081-101 study is to evaluate the safety and tolerability of a single subretinal injection of AAVB-081 in USH1B patients with retinitis pigmentosa due to a mutation in the MYO7A gene. The study will also assess the initial efficacy following AAVB-081 administration.
Participants needed: 15
Trial details
Phase: Phase 1, Phase 2Age: 18-50Biological sex: AllType: InterventionalSponsor: AAVantgarde Bio SrlUpdated: May 2, 2025Locations: 3
Eligibility criteria
Molecular diagnosis of USB1B due to MYO7A mutation [+1]
Unwillingness to meet the requirements of the study [+4]