Varus Deformity

2

Review clinical trials related to Varus Deformity. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Persona OsseoTi Keel Compatibility Study (Total Knee Arthroplasty)

The main objective of the study is to evaluate the safety, performance and clinical benefits of the Persona implant and its instrumentation in primary total knee arthroplasty

Participants needed: 760
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Zimmer BiometUpdated: Jan 20, 2026Locations: 16
Eligibility criteria

Patient is of legal age and skeletally mature [+3]

Patient is currently participating in any other surgical intervention or pain ma... [+13]

Status: Not yet recruiting

TO Plate Fixation vs. External Fixator Comparison (HTO Plate vs. ExFix Study)

This study aims to compare the efficacy, accuracy, and functional outcomes of two different surgical stabilization techniques for medial opening wedge high tibial osteotomy (HTO) in patients with varus deformity and medial compartment osteoarthritis. Patients will be prospectively randomized into two groups: Group 1 (Plate Fixation) will receive acute (single-stage) correction and stabilization with a medial HTO locking plate. Group 2 (HTO External Fixator) will receive stabilization using a self-adjusting HTO external fixator, followed by gradual correction (hemicallotasis/distraction) starting 7 days post-operatively. The study will evaluate radiological correction, functional improvement (using the Oxford Knee Score), and complication rates over a 12-month follow-up period.

Participants needed: 28
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Muhammed Cagatay EnginUpdated: Oct 23, 2025Locations: 1
Eligibility criteria

Varus malalignment associated with medial compartment degeneration/osteoarthriti...

Advanced-stage osteoarthritis (Indication for Total Knee Arthroplasty). Previous...