Status: Not yet recruiting
A Phase III Randomised Clinical Trial of Ultrasound Groin Monitoring Versus Groin Lymph Node Dissection to De-Escalate the Extent of Surgery in Vulvar Cancer
This study is a phase III, open label, multicentre, three-group, randomised clinical trial. The primary aim of this study is to determine whether intensive groin ultrasound monitoring (1) is effective and safe to replace invasive groin lymph node dissection (LND) to manage vulvar cancer, (2) decreases the morbidity associated with vulvar cancer surgery, and (3) is cost effective.
Participants needed: 640
Trial details
Phase: Phase 3Age: 18+Biological sex: FemaleType: InterventionalSponsor: Queensland Centre for Gynaecological CancerUpdated: Mar 24, 2026Locations: 9
Eligibility criteria
Females, over 18 years, with histologically confirmed SCC or adenocarcinoma of t... [+5]
Women with non-invasive vulvar conditions (e.g. non-invasive non-mammary Paget's... [+4]