Wellness, Psychological

8

Review clinical trials related to Wellness, Psychological. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Development and Validation of Single-Session Digital Self-Guided Intervention to Prevent Burnout & Improve Wellness

This study develops and evaluates a self-guided digital single-session mental health intervention designed to reduce workplace burnout and enhance psychological well-being among employed Canadian adults. Workplace burnout, characterized by emotional exhaustion, cynicism, and reduced professional efficacy, affects approximately 40% of Canadian employees and leads to increased absenteeism, reduced productivity, and higher disability claims. Traditional mental health supports face barriers including long wait times, stigma, and accessibility issues. Single-Session Interventions (SSIs) offer a practical, cost-effective, and scalable complement to traditional services. This is a randomized, double-arm, online trial. Participants are recruited via Prolific and randomly assigned (1:1) to either the experimental single-session burnout intervention or an active control condition focused on creative writing. The intervention focuses on its unique delivery of content focused on the evidence-based techniques, such as cognitive reframing, stress management, and behavioural strategies. The active control matches the intervention in length, structure, and user experience but omits the specific therapeutic ingredients. All procedures are conducted entirely online through Qualtrics. Participants are compensated for their participation. Participants complete three sessions over approximately 30 days: A baseline survey (about 10 minutes); A program session and immediate follow-up (about 40 minutes); And a 30-day follow-up survey (about 10 minutes). Outcome measures include burnout (MBI-16), perceived stress (PSS-10), depressive symptoms (PHQ-8), anxiety (GAD-7), general health (GHQ-12), well-being (WHO-5), work engagement (UWES-3), readiness to change, perceived impact, and program feedback/acceptability. Main outcomes are examined using mixed-effects linear regression with a participant-level random intercept to test the group × time interaction across baseline, post-intervention, and follow-up.

Participants needed: 250
Trial details
Age: 19+Biological sex: AllType: InterventionalSponsor: Saint Mary's University (Canada)Updated: May 13, 2026
Eligibility criteria

19 years of age or older [+4]

Being under 19 years of age [+3]

Status: Not yet recruiting

Impact of a Virtual Reality-based Mindfulness Program on Clinician Wellness

Burnout shares symptoms with anxiety and depression. While there is no single intervention for burnout, there are validated interventions (which are amenable to virtual reality (VR)) for anxiety and depression. UMassMemorial data from the Professional Well-Being Academic Consortium show that MD burnout and distress has increased since 2020. The investigators believe providing clinicians with a unique tool (VR) will be a feasible and efficacious way to tackle distress. It is known that only 1% of our MDs have done mindfulness training but nearly 50% are interested in doing so. Therefore, a self-administrable, interactive mindfulness program delivered over VR has great potential to reach clinicians who want to practice a more active form of mindfulness at a time convenient to them. The results of the study will provide preliminary evidence to determine if a take-home VR mindfulness program decreases clinician stress.

Participants needed: 32
Trial details
Biological sex: AllType: InterventionalSponsor: University of Massachusetts, WorcesterUpdated: Mar 13, 2026Locations: 1
Eligibility criteria

physician or APP employed by the Medical Group

Not willing to receive 2 texts per week

Status: Recruiting

Promoting Teenage Sleep for Improved Mental Health and School Performance

The overall aim of this project is to evaluate the effectiveness of two school-based programs that have the potential to promote adolescent sleep and prevent future depressive symptoms. The programs will be offered to students aged 13-19 at Swedish high schools and upper secondary schools at the classroom level. The students will be compared to teaching as usual (control group).

Participants needed: 3,000
Trial details
Age: 13-19Biological sex: AllType: InterventionalSponsor: Kristianstad UniversityUpdated: Mar 5, 2026Locations: 1
Eligibility criteria

Not listed

Status: Not yet recruiting

The INSPIRE Study: INvestigation of Swiss Physicians Inner-life, Resilience, and Emotions

The goal of this clinical trial, nested within an observational cohort study, is to evaluate whether two positive psychology web-based interventions can reduce emotional exhaustion and improve overall well-being in practicing physicians in Switzerland. The main questions it aims to answer are: Does participation in positive psychology interventions reduce emotional exhaustion at three months post-intervention? How do these interventions impact physician wellness, job satisfaction, comfort with end-of-life communication and other aspects of physicians' emotional well-being? Researchers will compare the effects of two intervention arms (general reflection vs. work-specific reflection) to a control group to determine whether focusing on work-specific aspects leads to greater improvements in emotional exhaustion and job-related outcomes. Participants will: * Complete an 8-day intervention consisting of positive psychology activities delivered online. * Complete baseline and follow-up assessments over the study period

Participants needed: 450
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: University of BernUpdated: Feb 13, 2026Locations: 1
Eligibility criteria

Be a practicing physician in Switzerland [+3]

Retired physician or physician seeking retirement within 3 years from first part... [+1]

Status: Recruiting

Effectiveness of GO for Transitional Housing Residents

The goal of this pre-post study is to enhance the health and wellness of the residents in the Concordia Tsat Sing Kong Transitional Housing Estate. This study aims to evaluate the effectiveness of the Green Oasis (GO) wellness program in: 1. Increase health awareness and engaging in health promoting activities, including more physical activities/walking, gardening. 2. Enhance happiness and quality of life. Participants will: * complete physical exercises, gardening, and interact with the GO website * receive health talks

Participants needed: 50
Trial details
Age: 10+Biological sex: AllType: InterventionalSponsor: The Hong Kong Polytechnic UniversityUpdated: Sep 11, 2025Locations: 1
Eligibility criteria

Aged 10 or above. [+4]

Have a serious organic disease or malignant tumor. [+2]

Status: Recruiting

Community Park-Based Programs for Health Promotion: The Fit2Lead Prospective Cohort Study

The Fit2Lead prospective cohort study examines the effects of a park-based youth mental health and resilience afterschool program on youth participant mental health, resilience, physical fitness, and violence prevention outcomes. Duke will perform a secondary analysis of the data collected as part of the Fit2Lead prospective cohort study run by Miami-Dade County Parks and Recreation.

Participants needed: 1,000
Trial details
Age: 12-17Biological sex: AllType: ObservationalSponsor: Duke UniversityUpdated: Sep 10, 2025Locations: 1
Eligibility criteria

All participants enrolled in the Miami-Dade Fit2Lead study will be included in t... [+1]

Anyone not enrolled in the Miami-Dade Fit2Lead study will be excluded from this... [+1]

Status: Not yet recruiting

Artificial Intelligence Powered Mental Health Support Tool For Physicians In Training

The purpose of this pilot study is to evaluate the acceptability of an artificial intelligence powered mental health support tool for mental health wellness amongst physicians in training. The primary research procedures are: The primary research procedure will be the utilization of artificial intelligence powered mental health support session through a web browser for physicians in training to address symptoms related to depression and anxiety. A pre and post intervention survey, evaluating depression symptoms with the standardized PHQ-9 questionnaire and anxiety symptoms with the standardized GAD-7 questionnaire will be conducted to assess changes in mental health wellness. The study will enroll physicians in training, including Internal Medicine residents and Gastroenterology fellows. The study includes at least 4 sessions. The total study duration for each subject is 3 months.

Participants needed: 20
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Cedars-Sinai Medical CenterUpdated: Jul 25, 2025Locations: 1
Eligibility criteria

Individuals 18 years old or older are included. [+2]

Active treatment of severe and uncontrolled anxiety or depression with a health... [+2]

Status: Recruiting

Teen Health Choices & Wellness

The goal of this observational study is to learn more about changes in health, wellness, and substance-use behaviors as teenagers get older. Participants, ages 13 to 16, will be asked to use a smartphone application developed for this research study. Participants will also come to Brown University or meet via video conference to answer questions about specific behaviors, choices, and feelings that may change over time.

Participants needed: 224
Trial details
Age: 13-16Biological sex: AllType: InterventionalSponsor: Brown UniversityUpdated: Apr 2, 2025Locations: 1
Eligibility criteria

be age 13 to 16 years [+3]

lifetime history of moderate or severe substance use disorder or treatment, excl... [+1]