Wild-Type Transthyretin-Related (ATTR)Amyloidosis

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Review clinical trials related to Wild-Type Transthyretin-Related (ATTR)Amyloidosis. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Phenotyping and Characterization of wtATTR-CM (TRACE 1)

Descriptive cross-sectional study on 100 consecutive ATTRwt-CM patients reflecting all NAC stages aiming primarily to investigate ATTRwt-CM patient's quality of life (QoL) measures and their relation to ATTRwt-CM severity. Secondarily aiming to investigate the possibility to measure misTTR and fragTTR in plasma and urine and to detect fragTTR in endomyocardial biopsies from ATTRwt-CM patients. To investigate whether misTTR and fragTTR levels are correlated with ATTRwt-CM severity.

Participants needed: 120
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Steen Hvitfeldt PoulsenUpdated: Aug 15, 2025Locations: 1
Eligibility criteria

endomyocardial biopsy [+2]

AL amyloidosis (light-chain amyloidosis). [+14]