Status: Recruiting
Phenotyping and Characterization of wtATTR-CM (TRACE 1)
Descriptive cross-sectional study on 100 consecutive ATTRwt-CM patients reflecting all NAC stages aiming primarily to investigate ATTRwt-CM patient's quality of life (QoL) measures and their relation to ATTRwt-CM severity. Secondarily aiming to investigate the possibility to measure misTTR and fragTTR in plasma and urine and to detect fragTTR in endomyocardial biopsies from ATTRwt-CM patients. To investigate whether misTTR and fragTTR levels are correlated with ATTRwt-CM severity.
Participants needed: 120
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Steen Hvitfeldt PoulsenUpdated: Aug 15, 2025Locations: 1
Eligibility criteria
endomyocardial biopsy [+2]
AL amyloidosis (light-chain amyloidosis). [+14]