Health Trials

X-linked Congenital Nephrogenic Diabetes Insipidus

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Review clinical trials related to X-linked Congenital Nephrogenic Diabetes Insipidus. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

A Study in Adult Males With X-linked Congenital Nephrogenic Diabetes Insipidus to Test the Effects of NDI-5001 Given for Multiple Days and to Test How NDI-5001 is Tolerated and Taken up in the Body

The primary purpose of this trial is to evaluate the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of NDI-5001 administered as a capsule following daily oral dosing in adult males with X-linked congenital nephrogenic diabetes insipidus (NDI) due to vasopressin receptor Type 2 (V2R) mutations.

Participants needed: 24
Trial details
Phase: Phase 1Age: 18-55Biological sex: MaleType: InterventionalSponsor: Otsuka Pharmaceutical Development & Commercialization, Inc.Updated: Apr 13, 2026
Eligibility criteria

X-linked congenital NDI with a genotype-confirmed arginine vasopressin receptor... [+1]

Participant who is not willing to follow a low-sodium (<=1 gram/day) diet during... [+5]

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