Status: Recruiting
Phase 3 Clinical Study Evaluating Efficacy, Safety, and Tolerability of Obicetrapib Vs Bempedoic Acid to Treat Dyslipidemia in Adults With Primary Non-familial Hypercholesterolemia or Mixed Dyslipidemia at High to Very High Cardiovascular Risk, During a Treatment Period of Approximately 84 Days
This Phase 3, randomized, double-blind, active-controlled study evaluates the efficacy and safety of obicetrapib (OBI) compared to bempedoic acid (BPA) in participants with dyslipidemia at high or very high cardiovascular risk. Participants must have elevated low density lipoprotein cholesterol (LDL-C) levels despite receiving maximally tolerated lipid lowering therapy. The primary objective is to compare the LDL-C lowering effect of OBI (a CETP inhibitor) against BPA at 12 weeks
Participants needed: 426
Trial details
Phase: Phase 3Age: 18+Biological sex: AllType: InterventionalSponsor: A. Menarini International Licensing S.A.Updated: Jun 9, 2026Locations: 1
Eligibility criteria
Are male or female and ≥18 years of age at Screening (Visit 1); [+8]
Have current or any previous history of New York Heart Association class III or... [+8]