Clinical trials

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Condition / disease
Location
Status: Recruiting

A Study of AIR-001 in Adults With Alpha-1 Antitrypsin Deficiency (AATD)

This is a Phase 1, open-label, single ascending dose (SAD) and multiple dose (MD) study of AIR-001 in participants with alpha-1 antitrypsin deficiency (AATD) due to PiZZ genotype.

Participants needed: 54
Trial details
Phase: Phase 1Age: 18-74Biological sex: AllType: InterventionalSponsor: AIRNA CorporationUpdated: Apr 28, 2026Locations: 4
Eligibility criteria

Male or female participants >18 years and <75 years of age at the time of signin... [+10]

Female participants who are nursing or lactating [+27]