Health Trials

Clinical trials

2

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Condition / disease
Location
Status: Not yet recruiting

To Establish the Safety and Effectiveness of the ALPFA GRAIL PFA System for Treating Symptomatic Benign Prostate Hyperplasia (BPH) Also Known as an Enlarged Prostate.

The main goal of this study is to evaluate the ALPFA GRAIL™ Pulsed Field Ablation (PFA) System for treatment of enlarged prostate (BPH) symptoms. The study will involve up to 250 male participants who have urinary problems caused by BPH and whom are greater than 40 years of age in up to 30 investigational centers across the US,Canada and European Union.

Participants needed: 250
Trial details
Age: 45+Biological sex: MaleType: InterventionalSponsor: ALPFA MedicalUpdated: May 18, 2026
Eligibility criteria

≥ 45 years of age on the day of enrollment. [+5]

History of clinically significant heart failure (NYHA III/IV) [+36]

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Status: Not yet recruiting

A Prospective, Single-Arm, Pilot Study of the ALPFA BPH PFA System in Men With Low, Intermediate and High-Risk Prostate Cancer

The primary objective of this study is to evaluate the safety and effectiveness of PFA in patients with localized prostate cancer.

Participants needed: 50
Trial details
Age: 45+Biological sex: MaleType: InterventionalSponsor: ALPFA MedicalUpdated: Apr 7, 2026
Eligibility criteria

Men ≥ 45 years of age on the day of enrollment with a life expectancy ≥10 years. [+18]

Patients with prostates previously treated with surgery (including minimally inv... [+9]

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