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Condition / disease
Location
Status: Recruiting

ADCX-020 for the Treatment of Patients With Locally Advanced or Metastatic Cancers

The purpose of this first-in-human study is to explore the safety, pharmacokinetics and effects of the study drug ADCX-020 in patients with advanced and metastatic solid tumors. ADCX-020 is an investigational anticancer therapy called antibody drug conjugate. This study is set up in multiple parts. In the first part of the study, participants receive increasing doses of ADCX-020. Then 2 or more doses will be assessed to identify the optimal dose. This optimal dose is subsequently evaluated for effect on different cancer types.

Participants needed: 290
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: Adcytherix SASUpdated: Jun 8, 2026Locations: 9
Eligibility criteria

Male and female participants ≥ 18 years of age [+6]

Known allergies/hypersensitivity/intolerance to or contraindication to exatecan,... [+6]