Clinical trials

1

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Safety and Efficacy of AIV007 Periocular Injection in Patients With Neovascular Age-Related Macular Degeneration

The goal of this study is to evaluate whether AIV007 provides benefits to patients with neovascular age-related macular degeneration in improving vision and that it has an acceptable safety profile. Participants will receive either a periocular injection of AIV007 or intravitreal injection of Eylea (control arm) to the study eye and return to the clinic monthly for safety and efficacy observations and/or continued treatment. Participants may receive additional treatment(s) if they meet specified criteria.

Participants needed: 35
Trial details
Phase: Phase 2Age: 50-85Biological sex: AllType: InterventionalSponsor: AiViva BioPharma, Inc.Updated: Apr 29, 2026
Eligibility criteria

Previously treated neovascular (wet) age-related macular degeneration (nAMD) [+5]

Study eye has had previous treatment with cell therapy, brachytherapy, and/or ge... [+8]