Clinical trials

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Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

IncobotulinumtoxinA (Xeomin) to Treat Focal Hand Dystonia

This study is a multicenter, double-blind, randomized placebo controlled, parallel group, superiority trial in order to test the superiority of intramuscular injections of IncobotulinumtoxinA against placebo using a 1:1 allocation ratio.

Participants needed: 48
Trial details
Phase: Phase 3Age: 18+Biological sex: AllType: InterventionalSponsor: Alain KaelinUpdated: Mar 19, 2026Locations: 5
Eligibility criteria

Informed Consent as documented by signature [+6]

Presence of spasticity, or other central sensorimotor lesion of motor system oth... [+11]

Status: Recruiting

Empathy and (Self-)Compassion in Parkinson's Disease Patients and Caregivers

The goal of this clinical trial is to improve quality of life in Parkinson's Disease (PD) patients by increasing their empathy and their (self-)compassion. The main question it aims to answer is: Does the level of quality of life in PD patients and caregivers improve after empathy/(self-)compassion training? Participants will be delivered a 6-week empathy and compassion training (mindfulness, writing and poetry exercises addressing the cognitive, emotional, motivational and behavioural components of (self-)compassion) and will also be asked to answer questionnaires before and after the training

Participants needed: 30
Trial details
Age: 50-80Biological sex: AllType: InterventionalSponsor: Alain KaelinUpdated: Dec 1, 2025Locations: 1
Eligibility criteria

Diagnosis of PD [+5]

Any medical condition that is not PD, such as drug induced parkinsonism [+8]

Status: Recruiting

Technical and Clinical Validation of the WPM-SEMG Prototype

Validation study designed to demonstrate the technical and clinical performance, and the safety of a new medical device in healthy volunteers and patients with myopathy or neuropathy. The medical device is the WPM-SEMG prototype designed for recording electrophysiological signals of muscles.

Participants needed: 70
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Alain KaelinUpdated: Sep 19, 2024Locations: 1
Eligibility criteria

* Healthy volunteers [+7]

Skin lesions in the area below the electrode [+24]

Status: Recruiting

Clinical Relevance of the HD sEMG Signals in the Post-stroke Rehabilitation

The goal of this clinical trial is to learn about the WPM-SEMG-V2 device (Wireless Portable and Multi-Channel, WPM) designated to acquire high-density (HD) surface electromyography (sEMG) signals in healthy volunteers and post-stroke patients. The main objectives are: 1) to technically and clinically validate the WPM-SEMG-V2 device in healthy volunteers; 2) to demonstrate the clinical relevance of the HD sEMG signals to support the process of rehabilitation of post-stroke patients. Participants will be asked to perform simple exercises using the muscles of the hand or the leg in static or dynamic contractions while wearing the WPM-SEMG-V2 device.

Participants needed: 40
Trial details
Age: 18-99Biological sex: AllType: InterventionalSponsor: Alain KaelinUpdated: Sep 5, 2024Locations: 1
Eligibility criteria

Written Informed Consent [+17]

Any significant acute disease state [+12]