Clinical trials

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Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Comparison of Breast Cancer Screening With CESM to DBT in Women With Dense Breasts

The over-arching goal of the Contrast-Enhanced Spectral Mammography Imaging Screening Trial (CMIST) is to determine if dual-energy contrast-enhanced spectral mammography (CESM) can detect more cancers with fewer false positives than digital breast tomosynthesis (DBT) in women with dense breasts. Aim 1: To evaluate the performance of CESM compared to DBT at baseline for breast-cancer screening in women with dense breasts. Aim 2: To evaluate the performance of CESM compared to DBT at the 1-year follow up for breast-cancer screening in women with dense breasts.

Participants needed: 2,032
Trial details
Age: 45-74Biological sex: FemaleType: InterventionalSponsor: American College of RadiologyUpdated: Feb 19, 2026Locations: 11
Eligibility criteria

1. Women must have mammographically dense breasts, ACR BI-RADS® lexicon categori... [+5]

1. Women currently undergoing treatment for breast cancer, or planning surgery f... [+15]

Status: Recruiting

National Mammography Database

The National Mammography Database (NMD) leverages data that radiology practices are already collecting under federal mandate by providing them with comparative information for national and regional benchmarking. Participants receive semi-annual feedback reports that include important benchmark data such as cancer detection rates, positive predictive value rates and recall rates. Participation in the NMD is free to Breast Imaging Center of Excellence (BICOE) facilities.

Participants needed: 8,000,000
Trial details
Age: 2-99Biological sex: AllType: ObservationalSponsor: American College of RadiologyUpdated: Oct 2, 2025Locations: 1Duration: 1 Year
Eligibility criteria

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