Clinical trials

2

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Available

An Expanded Access Protocol to Provide Avexitide in Patients With Post-Bariatric Hypoglycemia

The Expanded Access Program will provide access to avexitide for people with post-bariatric hypoglycemia (PBH) following Roux-en-Y gastric bypass (RYGB) who meet the eligibility criteria for this program. The safety of avexitide and patient treatment experience will be monitored during this program.

Trial details
Age: 18+Biological sex: AllType: Expanded AccessSponsor: Amylyx Pharmaceuticals Inc.Updated: May 13, 2026Locations: 1
Eligibility criteria

Category A: Individuals who have completed the LUCIDITY trial through the Week 4... [+9]

Use of GLP-1 receptor agonists, glucose-dependent insulinotropic polypeptide (GI... [+8]

Status: Recruiting

AMX0114 in Adult Participants With Amyotrophic Lateral Sclerosis

This study is a placebo-controlled Phase I study to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of the antisense oligonucleotide (ASO) AMX0114 in adult participants with amyotrophic lateral sclerosis (ALS).

Participants needed: 48
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: Amylyx Pharmaceuticals Inc.Updated: Apr 14, 2026Locations: 14
Eligibility criteria

Ability to understand the purpose and risks of this study, willingness to comply... [+7]

Presence of tracheostomy or permanent assisted ventilation. [+12]