Clinical trials

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Condition / disease
Location
Status: Recruiting

A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors

AGX101 is an antibody-drug conjugate (ADC) therapy for tumor-forming cancers. The purpose of this study is to learn about AGX101 effects and safety at various dose levels in an all-comers advanced solid cancer patient population. AGX101will be administered intravenously. Dosing of AGX101 will be repeated once every 3, 6 or 9 weeks. Participants may continue study treatment until disease progression, unacceptable toxicity, or consent withdrawal. Subjects will attend an end of treatment visit and will receive two safety follow-up telephone contacts up to 90 days following the last dose of study drug.

Participants needed: 80
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: Angiex, Inc.Updated: Feb 11, 2026Locations: 6
Eligibility criteria

Histologically confirmed unresectable, locally advanced, or metastatic solid tum... [+7]

Colorectal cancer patients with an unresected primary colorectal tumor and non-s... [+15]