Status: Recruiting
LSALT Peptide for Prevention or Attenuation of Acute Kidney Injury (AKI) in Patients Undergoing On-Pump Cardiac Surgery
To evaluate the percentage of subjects with AKI within 7 days following on-pump cardiac surgery defined by the KDIGO (Kidney Disease: Improving Global Outcomes) criteria: 1. Increase in baseline (pre-surgery) serum creatinine (SCr) by ≥26.5 μmol/L (≥0.3 mg/dL) within 7 days; OR 2. Increase in baseline SCr to ≥1.5 times baseline, which is known or presumed to have occurred within the first 7 days following surgery; OR 3. Urine output \< 0.5 mL/kg/h for \>6 hours.
Participants needed: 240
Trial details
Phase: Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Arch Biopartners Inc.Updated: Jun 12, 2026Locations: 9
Eligibility criteria
Male and female ≥ 18 years of age. [+15]
The presence of AKI (KDIGO criteria) at the time of randomization [+12]