Clinical trials

2

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Safety, Tolerability and Efficacy Study of ARCT-032 in People With Cystic Fibrosis

ARCT-032-02 is a Phase 2, open-label, multicenter, multiple-ascending dose study of ARCT-032 in adults with CF who are not eligible for CFTR modulator therapy or are not taking CFTR modulators due to drug intolerance, poor response, or lack of access to modulators.

Participants needed: 33
Trial details
Phase: Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Arcturus Therapeutics, Inc.Updated: May 8, 2026Locations: 13
Eligibility criteria

Confirmed diagnosis of Cystic Fibrosis [+2]

History of illness or medical condition that might pose an additional risk or ma... [+6]

Status: Recruiting

A Study to Evaluate the Pharmacodynamics and Safety of ARCT-810 in Participants With OTCD

Evaluate the safety and pharmacodynamics of multiple doses of ARCT-810 in adolescent and adult participants with OTC deficiency.

Participants needed: 9
Trial details
Phase: Phase 2Age: 12+Biological sex: AllType: InterventionalSponsor: Arcturus Therapeutics, Inc.Updated: Mar 17, 2025Locations: 1
Eligibility criteria

Willingness and ability to comply with all the protocol requirements, complete a... [+6]

Uncontrolled hypertension. [+19]