Clinical trials

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Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Role of Alprazolam in Management of Post Endodontic Pain After Single Visit Root Canal Treatment. To Compare Mean Pain Score Between Two Group of Participants Undergoing Post Operative Pain Management After Single Visit Root Canal Treatment: NSAIDs Alone and a Combination of NSAIDs and Alprazolam.

To compare mean pain score between two group of participants undergoing post operative pain management after single visit root canal treatment: one group receiving NSAIDs alone and the other receiving a combination of NSAIDs and an anxiolytic medication i.e alprazolam.

Participants needed: 110
Trial details
Age: 18-60Biological sex: AllType: InterventionalSponsor: Armed Forces Post Graduate Medical Institute (AFPGMI), RawalpindiUpdated: Dec 10, 2025Locations: 1
Eligibility criteria

patients aged between 18-60 years [+2]

patient suffering from systemic disease that requires antibiotics [+5]

Status: Not yet recruiting

This Study Compares Two Different Ways of Cleaning and Shaping Root Canals During Root-canal Treatment: the Step-down Technique and the Step-back Technique. Iu Want to Find Out Which Method Causes Less Pain After the Procedure. Patients Will be Randomly Placed Into One of the Two Groups, Treated Wit

This randomized clinical trial aims to compare the step-back and step-down root canal preparation techniques in patients with pulp necrosis. The study will evaluate which technique results in less postoperative pain. Participants will be randomly assigned to one of the two groups. Pain intensity will be recorded at specific time points after the procedure using a standardized pain scale. The goal is to identify the technique that provides better patient comfort after root canal treatment.This study is a randomized clinical trial designed to compare the effects of two root canal preparation techniques-step-back and step-down-on postoperative pain in patients diagnosed with pulp necrosis. Participants will be randomly assigned to one of the two groups.

Participants needed: 110
Trial details
Age: 18-65Biological sex: AllType: InterventionalSponsor: Armed Forces Post Graduate Medical Institute (AFPGMI), RawalpindiUpdated: Dec 18, 2025Locations: 1
Eligibility criteria

patients age between 18 to 65 years Healthy patients with ASA classification 1 a...

Patients with history of chronic pain Previously RCT treated tooth Teeth with ap...