Status: Recruiting
Study to Assess the Safety and Pharmacokinetics of AVD275 Injection in Patients With Osteoarthritis of the Knee
This study aims to understand the safety, drug concentration and distribution of an intra-articular injectable formulation of celecoxib, AVD275, in patients with knee osteoarthritis. One single injection at three different doses of the drug will be studied in a sequential order, and each participant will be monitored for 24 weeks over ten clinical visits.
Participants needed: 15
Trial details
Phase: Phase 1Age: 20-75Biological sex: AllType: InterventionalSponsor: Avidence TherapeuticsUpdated: Mar 31, 2026Locations: 1
Eligibility criteria
Written consent to participate in the study; Willingness and ability to comply w... [+10]
Any condition that could confound the patient's assessment of index knee pain in... [+26]