Clinical trials

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Condition / disease
Location
Status: Recruiting

Telacebec (T) Treatment in Adults With Buruli Ulcer (BU). (TREAT BU)

The goal of this interventional clinical trial is to demonstrate the complete BU lesion healing rate by 52 weeks after treatment initiation, without relapse and/or curative intent excision surgery, after 10-28 days of telacebec (T) treatment. Males and females age 18 and older will be included. • Participants will attend visits every 2 weeks during treatment and thereafter every 2 weeks until week 24 Thereafter they will be followed by visits at weeks 30, 40, and 52. From week 10 to week 52, if the lesion has healed, follow-up visits may be remote.

Participants needed: 200
Trial details
Phase: Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Barwon HealthUpdated: Jun 30, 2026Locations: 2
Eligibility criteria

Positive PCR or culture for confirmation of presence of mycobacterium ulcerans (... [+1]

Any non BU related condition where participation in the study, as judged by the... [+6]