Clinical trials

8

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Clinical Study of IM96 CAR-T Cell Therapy in Patients With Advanced Adenocarcinoma of Gastric/Esophagogastric Junction

This study, a single-center, open, single-dose clinical study, was designed to evaluate the safety and efficacy of IM96 CAR-T cells in treating patients with advanced adenocarcinoma of gastric/esophagogastric junction

Participants needed: 18
Trial details
Phase: Phase 1Age: 18-75Biological sex: AllType: InterventionalSponsor: Beijing Immunochina Medical Science & Technology Co., Ltd.Updated: Feb 13, 2026Locations: 1
Eligibility criteria

The age is 18 to 75 years (including boundary values) and the gender is not limi... [+13]

Presence of brain metastases; [+30]

Status: Not yet recruiting

Clinical Study Evaluating the Safety and Efficacy of IC19 CAR-T Cell Therapy for Refractory Systemic Lupus Erythematosus

This study is an open label, single arm exploratory clinical trial of IC19 CAR-T cell therapy for refractory systemic lupus erythematosus. Patients who are still in an active state after systemic treatment using the standard treatment regimen specified in the treatment guidelines were selected to receive IC19 CAR-T cell single pulse infusion therapy.

Participants needed: 6
Trial details
Phase: Early Phase 1Age: 18-70Biological sex: AllType: InterventionalSponsor: Beijing Immunochina Medical Science & Technology Co., Ltd.Updated: Mar 24, 2025
Eligibility criteria

Subjects diagnosed with systemic lupus erythematosus who meet the 2019 European... [+9]

Diseases of the central nervous system that have clinical significance in the pa... [+19]

Status: Not yet recruiting

Clinical Study of ZM001 Injection in the Treatment of Refractory Systemic Lupus Erythematosus

This is an open, single-arm, phase I clinical study of ZM001 in patients with refractory systemic lupus erythematosus

Participants needed: 18
Trial details
Phase: Phase 1Age: 18-70Biological sex: AllType: InterventionalSponsor: Beijing Immunochina Medical Science & Technology Co., Ltd.Updated: Feb 28, 2025
Eligibility criteria

Subjects with a diagnosis of systemic lupus erythematosus according to the 2019... [+21]

Pre-existing or clinically significant CNS disorders not due to lupus at the tim... [+19]

Status: Recruiting

Clinical Study of IM96 CAR-T Cell Therapy in Patients With Advanced Colorectal Cancer

This study, a single-center, open, single-dose clinical study, was designed to evaluate the safety and efficacy of IM96 CAR-T cells in treating patients with advanced colorectal cancer

Participants needed: 9
Trial details
Phase: Phase 1Age: 18-75Biological sex: AllType: InterventionalSponsor: Beijing Immunochina Medical Science & Technology Co., Ltd.Updated: Dec 5, 2024Locations: 1
Eligibility criteria

The age is 18 to 75 years (including boundary values) and the gender is not limi... [+10]

Presence of brain metastases; [+28]

Status: Not yet recruiting

IM19 CAR-T Cell Therapy for IgA Nephropathy Patients and Membranous Nephropathy Patients

IM19 CAR-T cell therapy for IgA nephropathy patients with urinary protein and renal dysfunction, as well as patients with intermediate to high-risk primary membranous nephropathy

Participants needed: 12
Trial details
Phase: Early Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: Beijing Immunochina Medical Science & Technology Co., Ltd.Updated: Nov 26, 2024
Eligibility criteria

IgA nephropathy [+11]

Kidney diseases other than IgA nephropathy, as well as primary and secondary nep... [+35]

Status: Not yet recruiting

WL276 CAR-T Cell Therapy for CD276 Positive Recurrent or Progressive Glioblastoma Patients

Clinical study evaluating the safety and efficacy of WL276 CAR-T cell therapy in CD276 positive recurrent or progressive glioblastoma patients

Participants needed: 6
Trial details
Phase: Early Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: Beijing Immunochina Medical Science & Technology Co., Ltd.Updated: Nov 18, 2024
Eligibility criteria

Diagnosed with glioblastoma through histopathological examination; [+8]

Those who require the use of immunosuppressants; Or individuals with autoimmune... [+19]

Status: Not yet recruiting

IM83 Clinical Study of CAR-T Cell Therapy in Patients With Relapsed or Refractory Osteosarcoma

The purpose of this study, a single-center, open, single-dose clinical study, was to evaluate the safety, tolerability, and pharmacokinetic profile of IM83 CAR-T cells in the treatment of patients with relapsed or refractory osteosarcoma

Participants needed: 9
Trial details
Phase: Phase 1Age: 16+Biological sex: AllType: InterventionalSponsor: Beijing Immunochina Medical Science & Technology Co., Ltd.Updated: May 14, 2024Locations: 1
Eligibility criteria

Age ≥ 16 years, both male and female; [+4]

Presence of brain metastases; [+22]

Status: Recruiting

Assessment of Safety and Efficacy of IM19 for Recurrent or Refractory (R/R) Non-Hodgkin's Lymphoma(NHL) Patients

This is a phase I/II, multicenter study to assess the efficacy and safety of IM19 CAR-T cells in adult with R/R Non-Hodgkins Lymphoma in China.

Participants needed: 52
Trial details
Phase: Phase 1, Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Beijing Immunochina Medical Science & Technology Co., Ltd.Updated: Dec 8, 2020Locations: 1
Eligibility criteria

Subjects with relapsed or refractory invasive non-Hodgkin's lymphoma, confirmed... [+7]

The investigators judged patients with gastrointestinal lymph nodes and/or centr... [+9]