Clinical trials

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Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

A Phase 2b Clinical Trial of YN001 in Adults With Coronary Atherosclerosis

This study is designed to evaluate the efficacy and safety of intravenously administered YN001 in patients diagnosed with coronary atherosclerosis, who are receiving background therapy for cardiovascular (CV) risk factors management.

Participants needed: 456
Trial details
Phase: Phase 2Age: 18-80Biological sex: AllType: InterventionalSponsor: Beijing Inno Medicine Co., Ltd.Updated: Apr 9, 2026Locations: 13
Eligibility criteria

Fully understands the purposes, features, and methods of the study and the possi... [+6]

Prior treatment with other investigational drug(s) within 30 days or 5 half-live... [+28]

Status: Recruiting

YN001-004 in Patients With Coronary Atherosclerosis in Australia

This study is to evaluate the efficacy and safety of intravenously administered YN001 in patients with coronary atherosclerosis in Australia. This study will be conducted in eligible participants with a diagnosis of coronary atherosclerosis, and at least 1 coronary artery is blocked determined by coronary computed tomography angiography (CCTA)

Participants needed: 24
Trial details
Phase: Phase 2Age: 18-75Biological sex: AllType: InterventionalSponsor: Beijing Inno Medicine Co., Ltd.Updated: Feb 17, 2026Locations: 7
Eligibility criteria

Fully understand the purposes, features, and methods of the study, and sign the... [+4]

Prior treatment with other investigational drug(s) within 30 days or 5 half-live... [+27]

Status: Not yet recruiting

Phase IIa Clinical Trial of YN001 in Patients With Atherosclerotic Cardiovascular and Cerebrovascular Diseases and Erectile Dysfunction

This is a randomized, double-blind, placebo-controlled phase IIa clinical trial to evaluate the efficacy and safety of YN001 in patients with atherosclerotic cardiovascular and cerebrovascular diseases and erectile dysfunction

Participants needed: 40
Trial details
Phase: Phase 2Age: 18-75Biological sex: MaleType: InterventionalSponsor: Beijing Inno Medicine Co., Ltd.Updated: Dec 30, 2025
Eligibility criteria

Fully understand the purpose, nature, method and possible adverse reactions of t... [+3]

Patients with erectile dysfunction caused by other sexual dysfunction diseases (... [+13]

Status: Not yet recruiting

Phase 1 Study of the Safety and Pharmacokinetics of YN001 With Rosuvastatin in Healthy Chinese Subjects

The primary objective of this study is to investigate the safety and tolerability of YN001 in combination with rosuvastatin, so as to provide evidence for the feasibility of YN001 combined with statins in subsequent clinical trials.

Participants needed: 24
Trial details
Phase: Phase 1Age: 18-55Biological sex: AllType: InterventionalSponsor: Beijing Inno Medicine Co., Ltd.Updated: Dec 30, 2025
Eligibility criteria

Fully understand the purpose, characteristics, research methods and potential ad... [+5]

Participation in other clinical trials within 3 months prior to the first dose o... [+25]

Status: Recruiting

A Pharmacokinetic Study of YN001 in Healthy Participants

This is a Phase 1, single-center, open-label study designed to evaluate the pharmacokinetics (PK), safety, and immunogenicity following a single dose administration in healthy adult volunteers.

Participants needed: 24
Trial details
Phase: Phase 1Age: 18-65Biological sex: AllType: InterventionalSponsor: Beijing Inno Medicine Co., Ltd.Updated: Dec 18, 2025Locations: 1
Eligibility criteria

Written informed consent must be obtained before any assessment is performed. [+8]

Received an investigational agent within 30 days or 5 half-lives (whichever is l... [+21]