Clinical trials

2

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Proof of Concept Study on BP1.4979 Effect on Essential Tremor

The goal of this clinical trial is to learn if drug BP1.4979 works to treat essential tremors in adults. It will also learn about the safety of drug BP1.4979. The main questions it aims to answer are: * Does the drug BP1.4979 reduce tremors in individuals with essential tremor? * Do participants have a good safety and tolerability of drug BP1.4979? Researchers will compare drug BP1.4979 to a placebo (a look-alike substance that contains no drug) to see if drug BP1.4979 works to treat essential tremors. Participants will: * Take the study drug (active or a placebo) twice daily over a 4-week period * Visit the clinic 5 times for health checkups and questionnaires completion over a period of approximately 7 to 10 weeks * Complete a diary weekly to assess the impact of essential tremor on daily life

Participants needed: 50
Trial details
Phase: Phase 2Age: 18-85Biological sex: AllType: InterventionalSponsor: BioprojetUpdated: Dec 16, 2025Locations: 14
Eligibility criteria

Male or female ≥18-85 years old [+3]

Severe tremor, defined as patient with ET characterized by a TETRAS-P score of ≥... [+6]

Status: Recruiting

Proof of Concept Study on BP1.4979 Effect on Primary Premature Ejaculation

The goal of this clinical trial is to learn if drug BP1.4979 works to treat primary premature ejaculation in adults. It will also learn about the safety of drug BP1.4979. The main questions it aims to answer are: * Does drug BP1.4979 increase the time to ejaculation during sexual intercourse? * Do participants have a good safety and tolerability of drug BP1.4979? Researchers will compare drug BP1.4979 to a placebo (a look-alike substance that contains no drug) to see if drug BP1.4979 works to treat primary premature ejaculation. Participants will: * Take drug primary premature ejaculation or a placebo per requested need prior to sexual intercourses for 12 weeks * Visit the clinic 4 times for checkups and questionnaires completion and have 2 phone calls with the study team over a period of about 17 weeks * Keep a diary of the intakes of the experimental drug, ejaculation time, ejaculation control, any unusual events concerning their health and any other medication taken

Participants needed: 60
Trial details
Phase: Phase 2Age: 18-50Biological sex: MaleType: InterventionalSponsor: BioprojetUpdated: Oct 6, 2025Locations: 1
Eligibility criteria

Males aged 18 to 50 years old (both inclusive) [+5]

Diagnosis of acquired PE, pseudo-PE or natural variable PE [+4]