Clinical trials

2

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

A Study to Investigate the Efficacy and Safety of Bemdaneprocel in Adults Who Have Parkinson's Disease

Study BRT-DA01-301 is a Phase 3 multicenter, randomized, sham surgery-controlled, double-blind study to assess efficacy and safety of bemdaneprocel in approximately 102 adults with Parkinson's Disease (PD).

Participants needed: 102
Trial details
Phase: Phase 3Age: 45-75Biological sex: AllType: InterventionalSponsor: BlueRock TherapeuticsUpdated: Jun 5, 2026Locations: 40
Eligibility criteria

Diagnosis of clinically established PD as defined by the International Parkinson... [+7]

PD presenting with recurrent falls [+11]

Status: Recruiting

A Study to Investigate the Safety of OpCT-001 in Adults Who Have Primary Photoreceptor Disease (CLARICO)

Study OpCT-001-101 is a Phase 1/2a first-in-human, multisite, 2-part interventional study to evaluate the safety, tolerability, and the effect on clinical outcomes of OpCT-001 in approximately 54 adults with primary photoreceptor (PR) disease. Phase 1 focuses on safety and features a dose-escalation design. Phase 2 is designed to gather additional safety data and assess the effect of OpCT-001 on measures of visual function, functional vision, and anatomic measures of engraftment in different clinical subgroups.

Participants needed: 54
Trial details
Phase: Phase 1, Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: BlueRock TherapeuticsUpdated: Apr 13, 2026Locations: 4
Eligibility criteria

Confirmed genetic diagnosis of primary photoreceptor (PR) disease [+2]

Clinically relevant, active ocular inflammation or infection [+10]