Clinical trials

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Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Long Term Follow-up Observational Study in Patients Treated with Gene-Modified T-Cell Therapy

This is a prospective long-term follow-up (LTFU) study to evaluate the long-term safety and survival benefit for patients who received at least one of CARsgen's GM T cell product in a clinical trial or as a commercially available product. In this study, patients will be followed for up to 15 years after last GM T-cell infusion for the evaluation of delayed adverse events (AEs), vector persistence, potential risk for integration, and survival time due to GM T-cell exposure.

Participants needed: 1,500
Trial details
Biological sex: AllType: ObservationalSponsor: CARsgen Therapeutics Co., Ltd.Updated: Feb 13, 2025
Eligibility criteria

There are no specific exclusion criteria for this study.

Status: Not yet recruiting

A Real-World Observational Study: Zevorcabtagene Autoleucel Injection in Patients with Relapsed/Refractory Multiple Myeloma

This study is a single-arm, open-label, multicenter, post-marketing, Phase IV, prospective, observational clinical trial to evaluate the efficacy and safety of the post-marketing product zevor-cel as treatment for subjects with R/R MM in the real world.

Participants needed: 200
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: CARsgen Therapeutics Co., Ltd.Updated: Oct 26, 2024
Eligibility criteria

Age ≥ 18 years; [+2]

Status: Recruiting

CT011 Autologous CAR-T Cells in Patients With Hepatocellular Carcinoma at Risk of Recurrence After Surgical Resection

A Single-arm, Open-label, Multicenter, Phase Ib Clinical Trial to Evaluate the Safety and Efficacy of CT011 Autologous CAR-T Cells in Patients with Hepatocellular Carcinoma at Risk of Recurrence after Surgical Resection.

Participants needed: 30
Trial details
Phase: Phase 1Age: 18-75Biological sex: AllType: InterventionalSponsor: CARsgen Therapeutics Co., Ltd.Updated: Aug 19, 2024Locations: 15
Eligibility criteria

Volunteer to participate in the clinical trial; fully understand and are informe... [+18]

Known fibrolamellar HCC, sarcomatoid HCC, or mixed hepatocellular-cholangiocarci... [+24]

Status: Recruiting

A Study to Evaluate the Efficacy and Safety of CT041 After Adjuvant Chemotherapy for Pancreatic Cancer

An open-label, single-arm, multicenter, Phase Ib clinical trial to evaluate the efficacy and safety of CT041 Autologous CAR T Cell Injection after adjuvant chemotherapy in subjects with pancreatic cancer.

Participants needed: 20
Trial details
Phase: Phase 1Age: 18-79Biological sex: AllType: InterventionalSponsor: CARsgen Therapeutics Co., Ltd.Updated: May 28, 2024Locations: 8
Eligibility criteria

Voluntary participation in the clinical trial; fully understand, be informed abo... [+11]

Prior neoadjuvant therapy for pancreatic cancer; [+23]

Status: Not yet recruiting

Anti-GPRC5D CAR-T Cells (CT071) in Participants With RRMM or RRpPCL

A Phase 1/2 Open label, multicenter, clinical trial of autologous CAR T-cell therapy targeting GPRC5D, in participants with relapsed/refractory multiple myeloma or relapsed/refractory primary plasma cell leukemia.

Participants needed: 166
Trial details
Phase: Phase 1, Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: CARsgen Therapeutics Co., Ltd.Updated: Mar 27, 2024
Eligibility criteria

Voluntarily signed consent; [+14]

Any significant condition(s), laboratory abnormality or psychiatric illness that... [+20]