Status: Recruiting
A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Anti-tumor Activity of CBI-1214 T Cell Engager in Participants With Advanced or Metastatic MSS/MSI-L Colorectal Cancer
This study will investigate the safety, tolerability, pharmacokinetics, and anti-tumor activity of CBI-1214 in participants with advanced or metastatic Microsatellite Stable (MSS)/Microsatellite Instability Low (MSI-L) Colorectal Cancer
Participants needed: 80
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: Cartography BiosciencesUpdated: Jun 10, 2026Locations: 8
Eligibility criteria
Participant with MSS/MSI-L CRC, who has exhausted at least one prior line of sta... [+3]
Participant whose CRC tumor tissues have been identified as dMMR or MSI-H [+9]