Clinical trials

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Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Evaluating a New Therapy for Dry Eye in Patients With Sjögren's Syndrome

This study will evaluate the effect of TRYPTYR in patients with Sjögren's syndrome-related dry eye disease. The goal is to determine whether TRYPTYR can improve symptoms and signs of dry eye in this specific patient population.

Participants needed: 35
Trial details
Phase: Phase 4Age: 18+Biological sex: AllType: InterventionalSponsor: Center For SightUpdated: Dec 22, 2025Locations: 1
Eligibility criteria

Adults over 18 years old with a diagnosis of dry eye disease (DED) secondary to... [+2]

History of ocular surgery within the past 6 months. [+6]

Status: Recruiting

Arcuate Incisions With Light Adjustable Lens for Astigmatism Correction in Lens Surgery

This study aims to evaluate the safety and effectiveness of femtosecond laser arcuate corneal relaxing incisions (AK) combined with Light Adjustable Lens (LAL) implantation for correcting pre-existing corneal astigmatism in patients undergoing cataract or refractive lens exchange surgery. Postoperative assessments will focus on residual refractive astigmatism, visual outcomes, patient satisfaction, and the incidence of adverse events. Arcuate keratotomy and toric IOLs are well-established methods for astigmatism correction, and this study will compare their combined effectiveness using advanced femtosecond laser technology.

Participants needed: 60
Trial details
Phase: Phase 4Age: 21+Biological sex: AllType: InterventionalSponsor: Center For SightUpdated: Dec 22, 2025Locations: 2
Eligibility criteria

Subject must be aged ≥ 21 years at the time of eligibility visit. [+7]

Subject who has undergone previous corneal or intraocular surgery in the eye to... [+15]

Status: Recruiting

Odyssey Evaluation in Post LASIK Patients

This prospective study evaluates the visual and refractive outcomes of the TECNIS Odyssey intraocular lens (IOL) implanted in patients with a history of myopic LASIK. Given the unique optical challenges of post-LASIK eyes, including altered corneal curvature and higher-order aberrations, the study aims to assess the IOL's performance in terms of distance, intermediate, and near vision, and patient satisfaction. Its design features may offer favorable outcomes in these patients.

Participants needed: 30
Trial details
Phase: Phase 4Age: 50+Biological sex: AllType: InterventionalSponsor: Center For SightUpdated: Dec 3, 2025Locations: 1
Eligibility criteria

Age: 50 years and older. [+7]

Established ocular pathology, including: glaucoma (except glaucoma suspects), uv... [+20]