Clinical trials

5

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Climate Anxiety in a Young Population at Risk of Suicide

Climate change has become a major source of concern, particularly among younger generations who are facing the progressive degradation of ecosystems, loss of biodiversity, and alarming environmental information disseminated through the media. The direct perception of climate-related disruptions has been shown to engender a profound sense of helplessness and loss. This distress, termed eco-anxiety, is characterised by feelings of fear, sadness and guilt regarding the planet's future. In a context where there has been a marked increase in suicidal thoughts and attempts among young people over the past decade, it is essential to explore the psychological manifestations of eco-anxiety within this vulnerable population. The paucity of studies investigating this association underscores the significance of the present research. The aims of this study is to examine the relationship between climate anxiety and suicidal risk among young people aged 16 to 24 years. The study will encompass 108 young participants aged between 16 and 24 years, who are either hospitalised or receiving outpatient psychiatric care. Each participant will be required to complete one clinician-administered assessment, namely the Columbia Suicide Severity Rating Scale (C-SSRS), and two self-report questionnaires: the Climate Change Anxiety Scale - French version (CCAS-FR) and the State-Trait Anxiety Inventory (STAI-Y). Furthermore, a sociodemographic questionnaire will be administered in order to collect information regarding the subjects' age, sex, education level, living conditions, and psychiatric history. It is hypothesised that there is a positive association between climate anxiety and suicidal risk, with the most eco-anxious participants showing higher C-SSRS scores. It is further predicted that eco-anxiety will correlate with elevated levels of state and trait anxiety, with the potential for modulating this relationship by sociodemographic factors, including gender. This study will contribute to a better understanding of the psychological impacts of climate change on young people and help identify the most vulnerable profiles.

Participants needed: 108
Trial details
Age: 16-24Biological sex: AllType: ObservationalSponsor: Centre Hospitalier EsquirolUpdated: Jun 4, 2026Locations: 1
Eligibility criteria

Men and women, boys and girls ; [+5]

Participants will not be included in the study if their health condition is inco... [+5]

Status: Recruiting

Sensory Profile of People With High Intellectual Potential (HIP)

This is a prospective observational psychology study on a non-clinical population, involving the use of questionnaires (non-interventional research). This study involves the collection of data associated with High Intellectual Potential characteristics, sensory profile, and includes clinical measures such as anxiety anxiety, autistic traits and coping in High Intellectual Potential and control participants.

Participants needed: 160
Trial details
Age: 18-65Biological sex: AllType: ObservationalSponsor: Centre Hospitalier EsquirolUpdated: Jul 24, 2025Locations: 1
Eligibility criteria

Participants with a High Intellectual Potential : Cognitive assessment using the... [+4]

History or declared psychiatric disorder (characterized depressive episode, pers... [+11]

Status: Not yet recruiting

Exploratory Study of Sensory Profile and Coping Strategies in Eating Disorders

This descriptive study aims primarily to characterize the sensory profile of patients with eating disorders (divided into three diagnostic groups: anorexia nervosa, boulimia nervosa and hyperphagia), controlling for possible autistic traits in this population. The study involves measuring characteristics associated with eating disorders (diagnosis, BMI, anxiety), assessing the sensory profile (AASP), and coping strategies in patients with eating disorders who are hospitalised or followed up in consultation.

Participants needed: 150
Trial details
Age: 18-65Biological sex: AllType: ObservationalSponsor: Centre Hospitalier EsquirolUpdated: Jun 22, 2025Locations: 1
Eligibility criteria

Gender and Age: Male or female, aged 18 to 65 [+3]

Psychiatric comorbidity (non-tobacco addiction, characterized depressive episode... [+8]

Status: Recruiting

Sensory Profile and Early Clinical Signs of Calm Room Users

This descriptive study aims primarily to characterize the sensory profile of patients in a closed psychiatric hospital unit who use a calming room. The main questions it aims to answer are : * Could sensory information processing disorders be the cause of distress and tension in these patients? * Could users of the calming room present extreme sensory processing profiles, characterized by either hypersensitivity or hyposensitivity ? Participants will answer a survey to determine their the sensory profile. Participants can already use the calming room as part of their regular medical care and they will answer surveys before and after each use.

Participants needed: 80
Trial details
Age: 18-65Biological sex: AllType: ObservationalSponsor: Centre Hospitalier EsquirolUpdated: Feb 21, 2025Locations: 1
Eligibility criteria

Gender and Age: Male or female, aged 18 to 65 [+3]

Inability to understand information related to the study [+6]

Status: Recruiting

Impact of Psychomotor Therapy on the Quality of Life in Depression

The effectiveness of psychomotor therapy in improving clinical outcomes or quality of life for individuals with depression is unclear. The investigators will assess how the participants' quality of life and psychomotor profile change over time. The study aims to compare the quality of life at 3 months between patients who received 3 months of personalised psychomotor therapy in addition to standard treatment and those who received standard treatment alone. The study lasted for 6 months, and the investigators expects a total of 128 people to participate in this research across several hospital establishments. This study evaluates the effectiveness of two types of treatment, divided into two randomly selected groups. To participate, individuals must have a medical diagnosis of major depressive disorder (MDD) and be between the ages of 20 and 60. They must have depressive symptoms with an HDRS score greater than 16 and provide informed consent. They must be treated or hospitalised at the Centre Hospitalier Esquirol or the Centre Hospitalier Henri Laborit (France). After providing consent, they will undergo an initial clinical interview that evaluates anxiety, self-esteem, pleasure, and quality of life. The therapist assessed the participant's muscle tone, gross motor skills, praxis, manual dexterity, rhythm, processing of sensory information, and body image. Following the assessment, the participant was randomly assigned to either the experimental or control group. The experimental group received the usual treatment for depression and underwent psychomotor therapy once a week for 12 weeks. The control group received the standard treatment for depression and underwent weekly telephone interviews. An assessment is scheduled at 1 month to evaluate the participant's health status, including any changes to treatment and assessment of anxiety and depressive symptoms. Another interim check-up is scheduled at 3 months to assess the patient's health status. The interview will also assess any changes to treatment, anxiety and depressive symptoms, quality of life, and psychomotor function. A final visit will be scheduled at 6 months for an assessment of the participant's health. The interview will also assess any changes to treatment, anxiety and depressive symptoms, quality of life, and psychomotor function.

Participants needed: 128
Trial details
Age: 20-60Biological sex: AllType: InterventionalSponsor: Centre Hospitalier EsquirolUpdated: Feb 19, 2025Locations: 1
Eligibility criteria

Diagnosis of depressive episode according to DSM-5 criteria. [+4]

Psychiatric comorbidity (non-tobacco addiction, eating disorders, bipolar disord... [+7]