Clinical trials

7

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

High Risk of Death or Disability in Brain Hemorrhage: Role of Spot Sign and Secondary Markers

This study looks at patients with brain hemorrhage to see if a special sign on brain scans, called the "Spot Sign," combined with other scan features, can predict a higher risk of death or disability. By comparing patient outcomes with existing prediction scores, the study aims to understand whether these scan markers provide extra value in identifying patients at higher risk.

Participants needed: 50
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Centre Hospitalier de GonesseUpdated: Sep 15, 2025Locations: 1
Eligibility criteria

Spontaneous intracerebral hemorrhage confirmed by contrast-enhanced CT scan. [+3]

Patient deceased before the initial contrast-enhanced CT. [+1]

Status: Recruiting

Eligibility of Patients Referred to Emergency Departments by Their General Practitioners for Care in Walk-in Clinics: A Single-Center Study in Île-de-France

This study aims to find out how many patients sent to the emergency department by their general practitioner could instead be treated in a walk-in clinic. Walk-in clinics provide quick, basic medical care without an appointment and can perform simple tests like blood work and X-rays. By identifying patients who don't need full hospital emergency care, this study hopes to improve patient flow and reduce overcrowding in emergency rooms in the Île-de-France region.

Participants needed: 80
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Centre Hospitalier de GonesseUpdated: Aug 14, 2025Locations: 1
Eligibility criteria

Age 18 years or older [+5]

Patients under 18 years old (pediatric cases excluded) [+8]

Status: Not yet recruiting

Predictive Factors for Initial MMSE Score and Rapid Decline in Alzheimer's Disease Patients

This study looks at people with Alzheimer's disease to find out which factors are linked to their initial score on the Mini-Mental State Examination (MMSE) and which factors may predict a fast decline in their score over 12 months. Researchers will review medical records from patients seen at the Memory Clinic of Gonesse Hospital and analyze information such as age, education, medical history, nutrition, mood, and caregiver burden. The goal is to better understand what influences early cognitive performance and how quickly it changes, to help improve patient care and planning.

Participants needed: 100
Trial details
Biological sex: AllType: ObservationalSponsor: Centre Hospitalier de GonesseUpdated: Aug 14, 2025Locations: 1
Eligibility criteria

Confirmed diagnosis of Alzheimer's disease according to NIAA 2018 or IWG 2021 cr... [+2]

Presence of other neurodegenerative diseases (e.g., Frontotemporal Dementia, Mul... [+1]

Status: Recruiting

Prognostic Value of Isolated and Combined Score Aspects in Acute Ischemic Stroke

This study, called TARGET-ASPECT, looks at patients who had a type of stroke called acute ischemic stroke and were treated with clot-busting medicine and a procedure to remove the clot. Even with these treatments, about half of patients don't fully recover. The study aims to see if certain brain imaging scores, especially when combined, can better predict how well patients will recover 90 days after their stroke and if their blood vessels reopen successfully. The study will include 152 patients and last about 9 months. The goal is to find easy and reliable tools that doctors can use to make better treatment decisions.

Participants needed: 152
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Centre Hospitalier de GonesseUpdated: Jul 16, 2025Locations: 1
Eligibility criteria

Patients aged 18 years or older [+3]

Primary hemorrhagic stroke [+2]

Status: Not yet recruiting

Assessment of Interprofessional Competencies of Healthcare Professionals Before and After Healthcare Simulation Sessions

The aim of our study is to assess the interprofessional competencies of healthcare learners before and one month after interprofessional simulation sessions, and to demonstrate their impact on the work of healthcare professionals as part of their continuing education in a hospital setting. Initially, we will distribute a self-assessment questionnaire to all learners before the simulation sessions and again one month after the sessions. Hospital-based healthcare professionals register for the simulation training through the continuing education department of Gonesse Hospital. Physicians and medical students register through the training's designated physician. Paramedical students register through the training's designated nurse manager. We conduct two simulation training sessions per month on the topic of "Adult Life-Threatening Emergencies: Cardiac Arrest." Each session is composed of an interprofessional group. Before the start of the session, the questionnaire is distributed to all participants. Learners are asked to indicate only their profession and the date on the questionnaire. Each questionnaire is assigned a number in the order of collection to ensure anonymity. One month later, we resend the same questionnaire by email to the participants. This is a self-assessment questionnaire developed in Canada and scientifically validated, used to evaluate interprofessional collaboration competencies (Survey for the Achievement of Interprofessional Collaborative Competencies: SACCI). In a second phase, we will compare the results of the self-assessment questionnaires completed before and one month after the simulation sessions, using statistical analysis via Excel spreadsheet.

Participants needed: 200
Trial details
Biological sex: AllType: ObservationalSponsor: Centre Hospitalier de GonesseUpdated: Jul 14, 2025Locations: 1
Eligibility criteria

Medical students (interns and externs) [+2]

Administrative staff [+1]

Status: Not yet recruiting

Screening for Cognitive Disorders in Multiple Sclerosis

This study aims to identify cognitive problems in adults with multiple sclerosis (MS). MS can affect memory, thinking speed, and spatial skills, which may impact daily life and work. We will use simple and proven tests to check for these difficulties and see how they affect quality of life. The study will include about 60 patients followed at the neurology day hospital.

Participants needed: 60
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Centre Hospitalier de GonesseUpdated: Jun 19, 2025Locations: 1
Eligibility criteria

Patients aged 18 years or older [+2]

Status: Not yet recruiting

Feasibility Study of a Relapse Investigation Questionnaire Administered by an MS Care Coordinator Nurse in Patients With Multiple Sclerosis

This study aims to evaluate a questionnaire used by a specialized nurse to help manage relapses in people with multiple sclerosis (MS). The questionnaire is completed during a phone call when the patient reports new or worsening symptoms. It helps the nurse decide whether further tests or treatments are needed, based on a protocol developed with a neurologist. The goal is to improve how quickly and effectively patients receive care during a relapse. The study will include 10 adult patients with active forms of MS over a two-month period.

Participants needed: 10
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Centre Hospitalier de GonesseUpdated: May 29, 2025Locations: 1
Eligibility criteria

Patients followed by Dr. Manchon for Relapsing-Remitting Multiple Sclerosis or a... [+2]

Pregnant women [+3]