Clinical trials

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Condition / disease
Location
Status: Recruiting

Pragmatic Trial of Psilocybin Therapy in Palliative Care

This multicenter, triple-blind, phase 2, randomized controlled trial will evaluate the efficacy and safety of psilocybin therapy compared to an active control in treating demoralization in adults near the end of life (≤2 years life expectancy).

Participants needed: 100
Trial details
Phase: Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Charles S. Grob, M.D.Updated: Nov 25, 2025Locations: 5
Eligibility criteria

Provision of signed and dated informed consent form and the capacity to consent... [+5]

Known allergic or severe reactions to the non-psychoactive components of psilocy... [+22]