Health Trials

Clinical trials

2

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

BN104 in Combination With Chemotherapy or Targeted Agents for Acute Myeloid Leukemia

The Phase I/II trial is to learn the safety, pharmacokinetics, and preliminary efficacy of BN104 taken twice daily combined with Intensive Chemotherapy or Venetoclax/Azacitidine in patients with acute myeloblastic leukemia.

Participants needed: 135
Trial details
Phase: Phase 1, Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Chen SuningUpdated: Dec 24, 2024Locations: 1
Eligibility criteria

Have been fully informed about the study and have voluntarily signed the ICF; [+11]

have active central nervous system (CNS) leukemia; [+15]

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Status: Recruiting

RDC-Blinatumomab Versus hyperCVAD for Ph-negative B-ALL.

In this study, newly diagnosed non-elderly patients with Philadelphia chromosomal negative (PH-) B-ALL were enrolled and 1:1 randomised into Reduced-intensity chemotherapy followed by Blinatumomab cohort or hyperCVAD cohort as induction therapy. The clinical remission rate, MRD negative rate and treaty-related adverse reactions were evaluated.

Participants needed: 124
Trial details
Phase: Phase 2Age: 15-65Biological sex: AllType: InterventionalSponsor: Chen SuningUpdated: Apr 4, 2024Locations: 1
Eligibility criteria

Age 15-65 [+6]

Ph+ (BCR-ABL1 positive) ALL [+9]

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