Clinical trials

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Condition / disease
Location
Status: Recruiting

Treatment of Newly Diagnosed Central Malignant Germ Cell Tumor People With Teniposide Injection Combined With Cisplatin.

This trial is a prospective single arm intervention study, conducting clinical research on marketed drugs. Adverse drug reactions are controllable and the risk is low, with an estimated total of 40 cases. The main objective is to evaluate the safety and efficacy of teniposide combined with cisplatin in the treatment of newly diagnosed central malignant germ cell tumors, and to conduct drug monitoring on subjects to explore potential biomarkers for predicting therapeutic efficacy. It is expected to ultimately achieve the goal of prolonging the overall survival of patients, while providing more guidance for the screening of the best treatment population and biological predictive markers.

Participants needed: 40
Trial details
Phase: Phase 2Age: 5+Biological sex: AllType: InterventionalSponsor: Chengcheng GuoUpdated: Sep 23, 2025Locations: 1
Eligibility criteria

Must have at least one measurable lesion defined by RANO criteria [+9]

Patients undergoing any other anti-cancer experimental treatment [+11]