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Condition / disease
Location
Status: Recruiting

The Effect of a Synbiotic on Intestinal Barrier Function and Microbiota Modulation in Middle-aged to Elderly Individuals With Excessive Body Weight

The study is a single-center, randomized, double-blind, placebo-controlled study in middle-aged to elderly adults with excessive body weight. The study includes an 8-week intervention period followed by a 2-week follow-up period. The study will evaluate the effect of a synbiotic consisting of two probiotic strains and a prebiotic. The aim is to investigate the effect of the synbiotic on modulating the gut microbiota and improving markers of gastrointestinal permeability and integrity and gastrointestinal discomfort.

Participants needed: 90
Trial details
Age: 50-70Biological sex: AllType: InterventionalSponsor: Chr Hansen - part of NovonesisUpdated: Apr 15, 2026Locations: 1
Eligibility criteria

Be able to give informed consent. [+7]

Has a history of drug and/or alcohol abuse. [+8]