Status: Recruiting
The Effect of a Synbiotic on Intestinal Barrier Function and Microbiota Modulation in Middle-aged to Elderly Individuals With Excessive Body Weight
The study is a single-center, randomized, double-blind, placebo-controlled study in middle-aged to elderly adults with excessive body weight. The study includes an 8-week intervention period followed by a 2-week follow-up period. The study will evaluate the effect of a synbiotic consisting of two probiotic strains and a prebiotic. The aim is to investigate the effect of the synbiotic on modulating the gut microbiota and improving markers of gastrointestinal permeability and integrity and gastrointestinal discomfort.
Participants needed: 90
Trial details
Age: 50-70Biological sex: AllType: InterventionalSponsor: Chr Hansen - part of NovonesisUpdated: Apr 15, 2026Locations: 1
Eligibility criteria
Be able to give informed consent. [+7]
Has a history of drug and/or alcohol abuse. [+8]