Clinical trials

2

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Condition / disease
Location
Status: Not yet recruiting

Nutrition Intervention Combined With Resmetirom for MASH

This randomized control trial aims to evaluate the effectiveness of combining resmetirom therapy (first approved pharmacological therapy for treating metabolic dysfunction-associated steatohepatitis (MASH)) with a nutritional intervention compared to resmetirom therapy alone over one year in improving liver health among 120 patients living with non-cirrhotic MASH. We hypothesize that patients receiving resmetirom and nutritional intervention will experience more significant improvements in liver function than those receiving only resmetirom therapy.

Participants needed: 120
Trial details
Phase: Phase 4Age: 18-75Biological sex: AllType: InterventionalSponsor: City University of New YorkUpdated: Jul 2, 2026Locations: 1
Eligibility criteria

Provide informed consent [+5]

Have cirrhosis or decompensated liver disease [+8]

Status: Recruiting

Transcranial Direct Current Stimulation (tDCS) With Verb Network Strengthening Treatment (VNeST) in Chronic Aphasia

The purpose of this study is to assess changes in language abilities of participants with chronic, post-stroke aphasia following an 8-week therapy period combined with brain stimulation. The investigators use a stimulation method called transcranial direct current stimulation (tDCS). The investigators cover two electrodes in damp sponges, place them on the scalp, and pass a weak electrical current between them. Some of this current passes through the brain and can change brain activity. One electrode is placed over language areas a bit above and in front of the left ear. The other is placed on the forehead above the right eye. Stimulation is provided twice a week for 8 weeks during aphasia therapy. The investigators believe that this stimulation may increase the effectiveness of therapy.

Participants needed: 30
Trial details
Age: 21-80Biological sex: AllType: InterventionalSponsor: City University of New YorkUpdated: Jan 7, 2025Locations: 1
Eligibility criteria

Right handed (pre-stroke for participants with aphasia) [+7]

Failed vision or hearing screening [+6]