Clinical trials

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Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Fueling Strong Hearts for a Strong South Carolina

South Carolina is home to many survivors of stroke. After leaving the hospital and finishing therapies, stroke survivors often do not have the supports they need to fully recover. Many live with problems for a long time after their stroke, such as trouble walking or doing everyday tasks like cleaning, grocery shopping, or cooking. Research suggests that healthy habits, like moving more, eating well, and being at a healthy weight, can improve most of these disabilities. These habits can be hard to form alone though, especially in rural areas that may not have many healthy foods or places to exercise. Research-based programs can help people form healthy habits. These programs have not been tested in stroke survivors who have different needs though. The goal of this research project is to test StrongPeople StrongHearts, a health program, to see if it helps stroke survivors in South Carolina make better choices for their health and improve their quality of life. The program will be delivered online so that survivors in rural areas can be in the program. One group will also receive a weekly grocery box tailored to their needs to improve access to healthy foods. This study could help increase access to research-based programs for stroke survivors who do not have the supports they did soon after their stroke. This step is important for stroke survivors' long-term health and quality of life, the mission of the American Heart Association.

Participants needed: 50
Trial details
Age: 45-80Biological sex: AllType: InterventionalSponsor: Clemson UniversityUpdated: Aug 26, 2025Locations: 1
Eligibility criteria

age 45-80 years; [+5]

unstable cardiac arrhythmias, hypertrophic cardiomyopathy, severe aortic stenosi... [+6]

Status: Recruiting

A Peer Recovery Coaching Intervention for Hospitalized Alcohol Use Disorder Patients

The project objective is to rigorously evaluate the effectiveness of a peer recovery coaching intervention (called RC-Link) in patients hospitalized with medical complications from alcohol use on recovery outcomes guided by the new NIAAA definition of recovery, examine mechanisms of heavy drinking using daily ecological momentary assessment (EMA), and determine the program's cost-effectiveness using an randomized controlled trial (RCT) design. The primary outcomes are frequency of heavy drinking, biopsychosocial functioning, and remission from AUD.

Participants needed: 750
Trial details
Age: 18-75Biological sex: AllType: InterventionalSponsor: Clemson UniversityUpdated: Aug 27, 2025Locations: 2
Eligibility criteria

Live within 50 miles of the recruitment and plan to stay in the area for at leas... [+2]

Unable to provide informed consent [+9]

Status: Recruiting

Trauma Screening/Referral and Interpersonal Violence Prevention for Women with Substance Use Disorders

The purpose of this project is to implement a pilot study to investigate the feasibility and preliminary efficacy of a peer support specialist delivered violence prevention program for women in substance use treatment. The program entails a posttraumatic stress disorder (PTSD) screening, resource referral, and two session interpersonal violence prevention protocol for 60 participants. In this single arm trial, women are recruited from three substance use treatment facilities. Participants complete baseline, post-intervention, one-month, and three-month follow-up assessments. Self-report surveys assess trauma exposure, knowledge and behaviors related to interpersonal violence, and intervention engagement.

Participants needed: 60
Trial details
Age: 18+Biological sex: FemaleType: InterventionalSponsor: Clemson UniversityUpdated: Sep 23, 2024Locations: 2
Eligibility criteria

Not listed