Health Trials

Clinical trials

4

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

A Study of CHS-114 (Tagmokitug) in Combination With Toripalimab and/or Other Treatments in Participants With Advanced Solid Tumors

The main purpose of this study is to evaluate the safety and preliminary efficacy of CHS-114 in combination with toripalimab and/or other standard of care (SOC) compound(s) in participants with advanced or metastatic solid tumors.

Participants needed: 154
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: Coherus Oncology, Inc.Updated: Jun 12, 2026Locations: 30
Eligibility criteria

At least 1 measurable lesion based on RECIST v1.1 as determined by the Investiga... [+16]

History of prior malignancy other than the cancer under study that is progressin... [+15]

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Status: Recruiting

A Study of Toripalimab in Combination With Cisplatin and Gemcitabine in Participants With Recurrent Metastatic Nasopharyngeal Cancer

This study aims to investigate toripalimab with chemotherapy in participants with nasopharyngeal cancer.

Participants needed: 100
Trial details
Phase: Phase 4Age: 12+Biological sex: AllType: InterventionalSponsor: Coherus Oncology, Inc.Updated: Apr 6, 2026Locations: 13
Eligibility criteria

EBER/EBV-negative (HPV+/-) [+3]

Disease that is suitable for local therapy administered with curative intent. [+3]

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Status: Recruiting

Study of CHS-114 in Participants With Advanced Solid Tumors

This is a Phase 1, open-label, first-in-human, dose-escalation and expansion study of CHS-114, a monoclonal antibody that targets CCR8, as a monotherapy in patients with solid tumors.

Participants needed: 87
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: Coherus Oncology, Inc.Updated: Mar 19, 2026Locations: 16
Eligibility criteria

Arms 1a, 1b, 2, and 3 [+21]

Arms 1a, 1b, 2, and 3 [+7]

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Status: Not yet recruiting

A Study of CHS-1000 in Participants With Advanced or Metastatic Solid Tumors

The primary purpose of this trial is to assess the tolerability and safety of CHS-1000 alone and in combination with toripalimab-tpzi in participants with advanced solid tumors.

Participants needed: 48
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: Coherus Oncology, Inc.Updated: Sep 19, 2024
Eligibility criteria

Histopathologically or cytologically confirmed diagnosis of advanced or metastat... [+2]

Concurrent enrollment in another clinical study or participation in another clin... [+2]

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