Health Trials

Clinical trials

2

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Condition / disease
Location
Status: Recruiting

Comparing The Safety And Efficacy Of DEFENCATH® In Reducing Central-Line Bloodstream Infections (CLABSIs) In Adults Receiving Total Parenteral Nutrition Through A Central Venous Catheter (CVC)

This is a Phase 3, randomized, double-blind, controlled, adaptive, 2-arm, multicenter study to demonstrate the efficacy and safety of DefenCath in adult participants receiving home Total Parenteral Nutrition (TPN) via Central Venous Catheter (CVC) compared with heparin.

Participants needed: 200
Trial details
Phase: Phase 3Age: 18+Biological sex: AllType: InterventionalSponsor: CorMedixUpdated: May 20, 2026Locations: 22
Eligibility criteria

Participants who are resident within the US and Türkiye. [+11]

Any participant unable or not willing to sign inform consent. [+23]

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Status: Recruiting

Open-Label Study to Assess Safety and Time to Catheter-related Bloodstream Infections (CRBSI) in Subjects From Birth to < 18 Years of Age

This study is a post-marketing approval requirement to assess the safety and time to Catheter-related Bloodstream Infections (CRBSI) of DefenCath in pediatric population (birth to less than 18 years of age) who are on chronic HD for kidney failure.

Participants needed: 36
Trial details
Phase: Phase 4Age: Up to 17Biological sex: AllType: InterventionalSponsor: CorMedixUpdated: May 19, 2026Locations: 6
Eligibility criteria

The investigator, or a person designated by the investigator, will obtain writte... [+17]

The participant has received systemic antibiotics within the last 14 days. Topic... [+22]

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