Clinical trials

2

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Condition / disease
Location
Status: Recruiting

CR-001 in Adult Participants With Locally Advanced or Metastatic Solid Tumors

The purpose of this study is to determine the safety and tolerability of monotherapy CR-001 and identify the maximum tolerated dose (MTD), and/or optimal biologic dose and Recommended Phase 2 Dose(s) (RP2D) in participants with locally advanced or metastatic solid tumors.

Participants needed: 290
Trial details
Phase: Phase 1, Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Crescent Biopharma, Inc.Updated: Jul 13, 2026Locations: 22
Eligibility criteria

Life expectancy ≥ 3 months [+12]

Has malignancies other than disease under study within the past 3 years [+12]

Status: Recruiting

CR-001 in Adult Participants With Locally Advanced or Metastatic Solid Tumors

The purpose of this study is to determine the safety and tolerability of monotherapy CR-001 and identify the maximum tolerated dose (MTD), and/or optimal biologic dose and Recommended Phase 2 Dose(s) (RP2D) in participants with locally advanced or metastatic solid tumors.

Participants needed: 290
Trial details
Phase: Phase 1, Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Crescent Biopharma, Inc.Updated: Jun 29, 2026Locations: 20
Eligibility criteria

Life expectancy ≥ 3 months [+12]

Has malignancies other than disease under study within the past 3 years [+12]