Clinical trials

2

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

"A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder"

The purpose of this study is to examine the efficacy, safety, and tolerability of CYB003 compared to matching placebo as adjunctive treatment in participants with MDD.

Participants needed: 220
Trial details
Phase: Phase 3Age: 18-85Biological sex: AllType: InterventionalSponsor: Cybin IRL LimitedUpdated: Jul 2, 2026Locations: 47
Eligibility criteria

Aged 18 to 85 years inclusive, at Screening [+10]

Current or previously diagnosed schizophrenia spectrum or other psychotic disord... [+22]

Status: Recruiting

A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder

The purpose of this study is to determine the efficacy, safety and tolerability of CYB003 compared to matching placebo as adjunctive treatment in patients with MDD. For more information about the EMBRACE study, including participating study locations, and to register your interest in learning more about participation, please visit the study website: https://embrace-mdd-trial.com/

Participants needed: 330
Trial details
Phase: Phase 3Age: 18-85Biological sex: AllType: InterventionalSponsor: Cybin IRL LimitedUpdated: Jun 30, 2026Locations: 68
Eligibility criteria

Age18 to 85 years. [+9]

Current or previously diagnosed schizophrenia spectrum or other psychotic disord... [+18]