Clinical trials

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Condition / disease
Location
Status: Recruiting

Anticoagulation-free VV ECMO for Acute Respiratory Failure

Currently international experts recommend therapeutic anticoagulation for veno-venous extracorporeal membrane oxygenation (VV-ECMO). Reports and case series suggest that the absence of therapeutic anticoagulation is safe for VV-ECMO. No randomized control trials have assessed this. The aim of this pilot study is to assess safety and feasibility of an "anticoagulation-free strategy" for veno-venous ECMO (VV-ECMO) in Acute respiratory distress syndrome (ARDS).

Participants needed: 40
Trial details
Phase: Phase 2, Phase 3Age: 18+Biological sex: AllType: InterventionalSponsor: Damian RatanoUpdated: Jan 16, 2026Locations: 1
Eligibility criteria

Adult patient with ARDS on VV-ECMO

Contraindication to anticoagulation with UFH (known heparin-induced thrombocytop... [+2]